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APS-1 in Italy shows diverse AIRE mutations and various autoimmune issues.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

New treatments for PCOS focus on insulin resistance and reducing testosterone levels, along with traditional hormone therapies.

Male faces age with more wrinkles and hair loss, influenced by both body changes and environmental factors.

Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.

Researchers found an RNA transcript that might help control a growth factor linked to tumor development.

Finasteride blocks progesterone's effect on absence seizures in rats.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Lifestyle changes are the first step in treating infertility in PCOS, followed by medications like clomiphene and metformin, and then surgery if needed.

The research suggests that the ZP4 gene is linked to egg development in women with PCOS but requires more study to understand its role in infertility.

Men with advanced liver disease and high oestrone and low testosterone levels have worse health outcomes.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

Finasteride helps protect brain in old male rats.

Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.

The new test can measure very small amounts of testosterone in hair, and grinding the hair up first gives more accurate results.

Some skin diseases and their treatments can negatively affect male fertility.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Chromium supplements don't help with weight loss or improve hormone and metabolism issues in people with polycystic ovary syndrome.

Don't combine abiraterone and spironolactone for prostate cancer treatment as it may worsen the disease.

Antiandrogens are the main treatment for hirsutism, with individualized care and safe, affordable options needed.

DHT affects testicular development and regulates spermatogenesis in some fish.

Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.

A young woman's symptoms suggested PCOS, but tests and surgery confirmed and treated a rare ovarian tumor, resolving her condition.

Prenatally androgenized ewes can model increased hair diameter in women with PCOS.