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The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

Capsaicin cream quickly relieved itching in two patients with brachioradial pruritus.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Various treatments, including FDA-approved drugs, natural products, and oral supplements, can help with hair loss, but a patient's medical history and potential allergies should be considered when choosing a treatment.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Spironolactone plus finasteride reduces hirsutism more effectively.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.

Curcumin and its derivatives can block an enzyme important for making testosterone, with one derivative being particularly strong.

The study found that urine metabolites M1b or M4 are the best indicators of ATD use in horses, with detection possible up to 77 hours in urine and 28 hours in blood.

A compound made by Pfizer can potentially stimulate hair growth and reduce oil production, making it a good candidate for topical use.

The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.

Compound 15a was effective in inhibiting 5α-reductase.

Immunosuppressive therapy helps manage autoimmune diseases but carries risks like infection and potential for malignancy.

Finasteride forms three new products under acidic stress.

The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.

Liposomes improve finasteride delivery for hair loss treatment, making it a promising option for topical use.

The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

Phyllanthus urinaria extract may help treat hair loss by blocking a hair-related enzyme.

The document concludes that early and personalized treatment for PCOS in adolescents is crucial to manage symptoms and prevent long-term health issues.

Lifestyle changes and clomiphene are first-line treatments for infertility in women with PCOS, with other options available if these fail.

Certain natural compounds called terpenes may help prevent prostate cancer.

The guide helps clinicians diagnose and manage hair loss, detailing examination techniques and treatments for different types of alopecia.