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Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Zinc is effective for treating various skin conditions, including warts and acne.

The study suggests certain ACE gene variations are more common in women with PCOS and may be linked to increased insulin resistance.

Genetic defects in androgen production are linked to male developmental disorders and are improving treatment understanding.

A woman's hair loss and other symptoms were due to a rare hormone deficiency treatable with steroids.

The testes produce important hormones like testosterone and others that play key roles in male body functions.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Frontal Fibrosing Alopecia involves disrupted cholesterol pathways, fibrosis, and increased mast cells.

Plant roots respond to fungus smells by possibly using certain proteins and a plant hormone to change root growth, but more research is needed.

Intravaginal testosterone cream improves sexual satisfaction and reduces vaginal discomfort in postmenopausal women on breast cancer treatment without affecting hormone levels.

Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Certain pesticides and fungicides can interfere with male hormone functions, potentially causing reproductive issues in male rats.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.