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The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Finasteride doesn't effectively treat hair loss in postmenopausal women.

PCOS is caused by both genetics and environmental factors like diet and obesity.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Androgens can both increase and decrease hair growth in different parts of the body.

Early diagnosis and treatment, using finasteride, minoxidil, or hair transplantation, improves hair loss outcomes.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Sebocytes play a key role in controlling androgen levels in human skin.

Dutasteride and finasteride may reduce sperm count and volume but don't affect movement or shape; effects are reversible after stopping.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Hair loss in men is common, treatable, but not curable.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

High androgen levels in young women with PCOS are linked to higher blood pressure.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.