25 citations,
November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
25 citations,
July 2013 in “Environmental Toxicology and Chemistry” Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.
25 citations,
November 2001 in “Kidney International” Male hormones worsen kidney transplant damage, but blocking them helps.
25 citations,
March 2000 in “Journal of Endocrinological Investigation” Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
24 citations,
January 2015 in “Annals of Dermatology” Herbal extracts may help hair grow and could be an alternative to synthetic hair loss treatments.
24 citations,
January 2008 in “KARGER eBooks” The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
24 citations,
September 1996 in “Mycoses” Androgenic steroids can slow down or stop the growth of certain skin fungi.
23 citations,
April 2021 in “Journal of Clinical Medicine” Frontal Fibrosing Alopecia's cause is unclear, affects mainly postmenopausal women, and current treatments focus on stopping hair loss rather than regrowth.
23 citations,
February 2020 in “PLOS genetics” Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.
23 citations,
October 2018 in “Expert Opinion on Drug Safety” Consider benefits and risks of new alopecia treatments for safety.
23 citations,
June 2017 in “Drug Design Development and Therapy” Cyclodextrins improve finasteride's solubility and bioavailability for hair loss treatment.
23 citations,
June 2015 in “Clinica Chimica Acta” Researchers found potential urine markers for polycystic ovary syndrome, including testosterone-glucuronide and 11α-hydroxyprogesterone, which may help diagnose the condition.
23 citations,
December 2013 in “Regenerative Medicine” Hair follicle culture helps develop new treatments for hair loss.
23 citations,
December 2012 in “ChemistryOpen” Probe detects finasteride with high selectivity and low detection limit.
23 citations,
February 1979 in “Veterinary Clinics of North America: Small Animal Practice” Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.
22 citations,
October 2019 in “Cerebral cortex” Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.
22 citations,
November 2018 in “Brazilian Journal of Pharmaceutical Sciences” New physical methods like electrical currents, ultrasound, and microneedles show promise for improving drug delivery through the skin.
22 citations,
March 2012 in “Molecular Medicine Reports” DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.
22 citations,
August 2011 in “Journal of Supercritical Fluids” Rice bran extract might help prevent hair loss.
22 citations,
February 2010 in “The Veterinary clinics of North America. Small animal practice/Veterinary clinics of North America. Small animal practice” The cause of atypical Cushing's syndrome in dogs, possibly linked to sex hormones, is not yet proven.
22 citations,
April 1998 in “Dermatologic Clinics” Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.
21 citations,
November 2022 in “Frontiers in immunology” Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
21 citations,
May 2016 in “The Cochrane library” Topical minoxidil helps treat female pattern hair loss, but more research needed for other treatments.
21 citations,
April 2016 in “Journal of Dermatological Treatment” Finasteride may cause mental and sexual side effects, with hand preference and sexual orientation possibly affecting severity.
21 citations,
November 2014 in “Journal of Endocrinological Investigation” Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.
21 citations,
April 2012 in “European Journal of Pharmaceutics and Biopharmaceutics” The gel with special fat-loaded particles from rice bran could be an effective skin treatment for hair loss.
21 citations,
January 2012 in “Journal of Pharmaceutical Sciences” Desolvation of finasteride depends on environment and technique.
21 citations,
January 2003 in “Seminars in reproductive medicine” The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.
21 citations,
August 1994 in “Clinical endocrinology” 5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.
20 citations,
September 2020 in “Journal of Translational Medicine” Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.