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New compounds were made that effectively block a specific enzyme related to androgen conditions.

A new, less toxic and more efficient method to create the anti-baldness compound RU58841 was developed in 2014.

A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

The document reviews various hair and nail disorders, their causes, and treatments, emphasizing the need for proper diagnosis and the link between nail changes and systemic diseases.

Dutasteride may protect the brain in early Parkinson's disease.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.

The study found that urine metabolites M1b or M4 are the best indicators of ATD use in horses, with detection possible up to 77 hours in urine and 28 hours in blood.

Finasteride inhibits enzyme activity in rhesus macaques, suggesting they're useful for evaluating similar drugs.

New hybrid compound found to effectively prevent hair loss.

Targeting CD200 could be a new treatment for rheumatoid arthritis.

New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.

The research shows that hydrogen bonds greatly affect the crystal structure of a Finasteride derivative.

The removed ovarian tumor was a rare type of blood vessel tumor that improved the patient's symptoms and hormone levels after surgery.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Zouboulis syndrome is a rare condition that helps diagnose monosomy 18p early.

Hirsutism in women often indicates a hormonal imbalance and can be managed with a combination of hormonal treatments and hair removal methods.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

Finasteride's molecular and crystal structures help develop new drug formulations.