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Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Some new progesterone derivatives are better at blocking testosterone conversion than a common drug.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

New steroids were patented as effective for treating acne, hair loss, and other conditions related to hormones.

Certain drugs change freshwater snail shells to a "banana" shape.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Acne keloidalis nuchae is a tough-to-treat condition that greatly affects quality of life, especially in men of African descent.

Polycystic Ovary Syndrome (PCOS) is a hormonal disorder in women that can cause infertility and other health issues, and it may be improved by treatments that increase insulin sensitivity.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Different forms of hair loss drug can improve effectiveness.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.

Baicalin may help reduce excessive male hormone levels in PCOS.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

The document emphasizes early detection and treatment of men's skin conditions and recommends protective measures and appropriate treatments for different age groups.

Covers common skin issues in kids, their diagnosis, treatment, and need for specialist care.

Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.