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Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Finasteride doesn't affect antipyrine metabolism, so interactions with cytochrome P-450 enzyme drugs are unlikely.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

New compounds may help treat prostate cancer by reducing cell growth.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

Finasteride effectively blocks enzyme causing male pattern baldness.

Finasteride and minoxidil together promote hair growth better than either alone.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Finasteride doesn't affect erections much, but may decrease libido in men.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Dutasteride is more efficient than finasteride, but individual results vary.

Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.

Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.

The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Taking oral testosterone with finasteride or dutasteride doubles testosterone levels, and food slightly affects it.

Post-finasteride syndrome causes sexual, physical, and psychological symptoms, but more research is needed to understand its causes and connection to finasteride.

Finasteride blocks progesterone's effect on absence seizures in rats.