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Scientists made new substances that can block an enzyme linked to prostate issues and hair loss, with potential for creating a new treatment.

Compound 4 is a promising treatment for hair loss with low toxicity.

Teak leaf extract contains compounds that could help treat hair loss.

Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Androgenetic alopecia is a common hair loss condition caused by testosterone effects on hair follicles, leading to thinner, shorter, and less pigmented hair, diagnosed using scalp dermoscopy and treated with topical minoxidil, antiandrogen agents, and 5-alpha reductase inhibitors.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

The study found that the enzyme linked to acne is present in the same areas of both acne-affected and normal skin.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Finasteride and dutasteride are effective for male hair loss and enlarged prostate but may cause reversible sexual side effects.

Germacrene analogs, especially 8-Hydroxy germacrene B, are more effective than germacrone at blocking a hormone-related enzyme and could help treat hair loss.

Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Heredity and hormones cause common hair loss, and topical minoxidil is the first recommended treatment.

Minoxidil and finasteride effectively treat hair loss.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

New oral treatment, finasteride, effectively and safely treats common hair loss.

New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Asparagus racemosus root extract reduced sebum and pore size in men but not in women.

Some common medications can harm male fertility, but many effects can be reversed.

Female pattern hair loss is common, linked to polycystic ovarian syndrome, and treated with topical Minoxidil.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Rice husk and bran extracts from the Bue Bang 3 CMU variety can potentially treat hair loss due to their antioxidant, anti-inflammatory, and anti-androgenic properties.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.