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5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

The developed model can predict effective 5-alpha-reductase enzyme inhibitors.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

Medicines for enlarged prostate may raise the risk of breast growth and tenderness but not breast cancer.

Finasteride doesn't affect erections much, but may decrease libido in men.

Finasteride and minoxidil together promote hair growth better than either alone.

Testosterone and dihydrotestosterone play a role in women's health issues like excess hair and baldness, and treatments blocking these hormones may help.

The body's change of testosterone into DHT is not necessary for testosterone's muscle and sexual effects.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.

Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Using 5-alpha-reductase inhibitors, drugs for prostate issues and hair loss, may lead to eye abnormalities in men.

5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.

Dutasteride is more efficient than finasteride, but individual results vary.

Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

The document concludes that the risk of sexual side effects from 5-alpha-reductase inhibitors is low and often temporary, but more research is needed on potential permanent effects.

Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.

Inhibitors of the enzyme 5 alpha-reductase could potentially treat disorders like prostate cancer and baldness.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

New liposome treatment successfully delivers CRISPR to deactivate a key enzyme in androgen-related disorders.

5α-reductase inhibitors increase the risk of sexual dysfunction, especially in men with enlarged prostate.

Researchers found new potential but less potent rat enzyme inhibitors using a 3D model.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

Dutasteride is more effective than Finasteride in reducing prostate size and PSA levels, but both drugs have similar side effects.