4 citations,
January 2021 in “Cell transplantation” Scientists found the best time to transplant human stem cells for hair growth is between days 16-18 when they have the right markers and growth potential.
28 citations,
March 2010 in “Histochemistry and Cell Biology” Different markers are found in stem cells of the scalp's hair follicle bulge and the surrounding skin.
10 citations,
May 2020 in “Frontiers in cell and developmental biology” MicroRNAs are important for hair growth regulation, with Dicer being crucial and Tarbp2 less significant.
20 citations,
December 2010 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Decreased CD200 in hair follicles may cause immune issues in some alopecia areata cases.
July 2022 in “Journal of Investigative Dermatology” Cyclohexyl salicylate promotes human hair growth and increases certain hair follicle stem cell progeny.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” PPARγ signaling modulation can protect hair follicle stem cells from chemotherapy-induced damage.
688 citations,
June 2007 in “Cell Stem Cell” Removing the ATR gene in adult mice causes rapid aging and stem cell loss.
26 citations,
July 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The protein Par3 is crucial for healthy skin, affecting the skin barrier, cell differentiation, and stem cell maintenance.
23 citations,
May 2013 in “Virology” HPV16 oncogenes disrupt the normal activity of hair follicle stem cells.
2 citations,
August 2012 in “Cell Stem Cell” The study showed that some hair follicle stem cells wake up to grow hair while others stay asleep, and that the environment around them is important for hair growth.
63 citations,
April 2010 in “Development” Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.
7 citations,
June 2020 in “npj regenerative medicine” GDNF helps grow hair and heal skin wounds by acting on hair stem cells.
April 2023 in “Journal of Investigative Dermatology” Defective T cell metabolism can cause early skin aging and poor hair follicle stem cell function.
September 2016 in “Journal of Dermatological Science” The protein aPKCλ is crucial for keeping hair follicle stem cells inactive and for hair growth and regeneration.
14 citations,
July 2016 in “Anatomical Science International” The study suggests that the arrector pili muscle is important for hair health and its damage might contribute to hair loss.
7 citations,
January 2016 in “Laboratory Investigation” TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
96 citations,
July 2014 in “Cold Spring Harbor Perspectives in Medicine” The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.
80 citations,
September 2007 in “Cell Cycle” Stem cells in hair follicles can become various cell types, including neurons.
3 citations,
April 2011 in “Expert Review of Dermatology” Male hair loss is caused by inactive hair follicle stem cells.
1 citations,
January 2020 in “Microscopy research” Researchers successfully grew hair follicle stem cells from mice and humans, which could be useful for tissue engineering and regenerative medicine.
17 citations,
July 2013 in “Amino Acids” Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.
15 citations,
February 2009 in “Cell Stem Cell” The document concludes that certain chemicals can help maintain stem cell pluripotency and that understanding cell states is crucial for tissue regeneration.
May 2015 in “Journal of Investigative Dermatology” Wnt-3a helps grow more skin stem cells, which could lead to new hair loss treatments.
351 citations,
February 2010 in “Nature Cell Biology” Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.
16 citations,
August 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” MED1 is essential for normal hair growth and maintaining hair follicle stem cells.
8 citations,
September 2002 in “Genes to Cells” Killing specific cells in hair follicles can lead to hair growth problems in mice.
October 2015 in “CRC Press eBooks” Hair cloning for hair loss is not yet a practical solution.
August 2012 in “Nature Cell Biology” Hair grows when stem cell offspring in the follicle base proliferate, influenced by the dermal papilla.
156 citations,
October 2012 in “Seminars in Cell & Developmental Biology” Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
February 2021 in “Journal of The American Academy of Dermatology” Fibrosis in the bulge area of hair follicles can cause hair thinning in male pattern baldness, and drugs that inhibit fibrosis might help reverse this.