17 citations
,
July 2019 in “Majalah Obat Tradisional” This study found that tannin effectively inhibits and degrades mono-species and polymicrobial biofilms, making it a potential candidate for antibiofilm treatments.
June 2025 in “Formosa Journal of Sustainable Research” In this study, the NADES extract of mangkokan leaves (Polyscias scutellaria) demonstrated antibacterial activity against Escherichia coli and Staphylococcus aureus, with a total flavonoid content measured at 4.944 mgEQ/gSimplisia using the disc diffusion method.
January 2022 in “JPK Jurnal Proteksi Kesehatan” This study found that the ethanol extract of mangkokan leaf (Polyscias scutellarium) demonstrated antibacterial activity against Escherichia coli and Staphylococcus aureus, with higher concentrations showing greater inhibition zones, particularly against Staphylococcus aureus.
365 citations
,
November 2018 in “Journal of Allergy and Clinical Immunology” This review discusses the role of the skin microbiome in maintaining health and modulating atopic dermatitis, emphasizing the need for novel therapeutic strategies, but reports no new clinical results.
194 citations
,
October 2018 in “Microbiome” This study examined recent findings on the role of host-microbiome interactions in acne, highlighting that the skin's microbiome composition differs between acne-affected and healthy individuals and discussing emerging microbiome-based treatments.
129 citations
,
November 2005 in “Internal Medicine Journal” This article reviews the recognition and management of Staphylococcus aureus toxin-mediated diseases, but it does not present new research findings.
99 citations
,
June 2011 in “Journal of biomedical materials research. Part A” This study observed that keratose hydrogels sustained ciprofloxacin release over three weeks and inhibited Staphylococcus aureus growth in vitro for 23 days and in mice for 2 weeks.
96 citations
,
December 2018 in “Immunity” This study found that inhibiting TGF-β receptors in adult dermal fibroblasts restored their function and increased resistance to Staphylococcus aureus infection by enhancing their adipogenic and antimicrobial capabilities.
87 citations
,
July 2007 in “British Journal Of Nutrition” In this study, oral administration of Lactococcus lactis strain H61 to senescence-accelerated mice was linked to reduced bone density loss, less skin ulcer incidence, and reduced hair loss, along with altered immune responses.
74 citations
,
September 1980 in “Medical Clinics of North America” This article discusses toxic epidermal necrolysis, highlighting its high mortality rate despite aggressive treatment, and notes controversy over using high-dose systemic corticosteroids as therapy.
53 citations
,
April 2021 in “Cell Host & Microbe” This study found that skin microbiota, particularly in wild-type mice, promotes wound-induced hair follicle neogenesis and wound healing, highlighting the potential downsides of routine antibiotic use on skin regeneration.
49 citations
,
February 2014 in “Clinical Cosmetic and Investigational Dermatology” This review discusses the diagnostic and therapeutic approaches to furunculosis, emphasizing the importance of hygiene and microbiological testing to prevent and manage recurrent infections, and reports no new clinical results.
48 citations
,
April 2019 in “PloS one” This study observed a microbial shift on the scalp of Alopecia areata patients, characterized by an increase in Propionibacterium acnes and a decrease in Staphylococcus epidermidis, compared to healthy controls.
39 citations
,
July 2000 in “British Journal of Dermatology” This report on identical female twins with folliculitis decalvans suggests a possible genetic component to the disease, marking the first such case in twins.
37 citations
,
December 2024 in “Theranostics” In this study, a newly developed nanoparticle-loaded hydrogel wound dressing demonstrated significant antibacterial, antioxidant, anti-inflammatory, and proangiogenic activities, effectively reducing pain and promoting healing in a murine burn wound model while preventing infection by *Staphylococcus aureus*.
37 citations
,
March 1990 in “The Journal of Pediatrics” Toxic shock syndrome is caused by a complex interaction of bacterial toxins and the immune system, and understanding this can help improve diagnosis and treatment.
35 citations
,
November 2021 in “Journal of nanobiotechnology” This study reported that thymol-loaded nanoparticles showed promise as an antibiotic-free treatment for acne by effectively targeting the infection without disrupting healthy skin microbiota.
33 citations
,
September 2018 in “Frontiers in Microbiology” This study demonstrated that human hair shafts can inhibit the growth of Gram-positive bacteria but have no effect on Gram-negative bacterial growth, offering insights into hair and scalp health.
18 citations
,
June 2016 in “British Journal of Dermatology” This study found that bacterial biofilms were present in only two out of ten acute hidradenitis suppurativa lesions examined, suggesting a limited primary role for biofilms in early-stage lesions.
15 citations
,
March 2019 in “Veterinary Dermatology” This study found that three mousse products containing chlorhexidine and varying antifungal components maintained significant antibacterial activity against S. pseudintermedius in vitro for up to 10 days, while other mousses did not show significant differences.
14 citations
,
September 2009 in “International Journal of Dermatology” This study found a potential link between staphylococcal carrier status and dermatitis cruris pustulosa et atrophicans, a chronic folliculitis primarily affecting the legs.
13 citations
,
July 2016 in “Veterinary Dermatology” In this study on dogs, topical antimicrobial sprays with varying ingredient profiles showed different levels of S. pseudintermedius growth inhibition, maintaining activity for at least 10 days.
13 citations
,
May 2010 in “Dermatologic Clinics” Recurrent furunculosis can be managed with antibiotics, decolonization, and decontamination, with potential future use of vaccines and bacteriophage therapy.
13 citations
,
November 2017 in “BMC Veterinary Research” This study suggests that topically applied fusidic acid may penetrate only the most superficial layers of canine skin but can reach sufficient concentrations to potentially treat infections caused by pathogenic staphylococci.
11 citations
,
October 2017 in “Mycoses” In this case report, an 80-year-old male with severe sycosis barbae and no animal contact was successfully treated with oral terbinafine after diagnostic sequencing identified Trichophyton verrucosum as the infecting species.
11 citations
,
August 2009 in “Dermatologic Surgery” A man developed a rare scalp disorder, Folliculitis Decalvans, 20 years after hair restoration surgery, and it required long-term antibiotic treatment.
11 citations
,
January 2009 in “Indian journal of dermatology, venereology, and leprology” This review discusses the characteristics, geography, and treatment challenges of dermatitis cruris pustulosa et atrophicans in men, emphasizing the need for further research on its etiology and management; it presents no new clinical findings.
9 citations
,
January 2015 in “Indian Dermatology Online Journal” This case report highlights the successful treatment of Kaposi varicelliform eruption in a pemphigus vulgaris patient using intravenous acyclovir, alongside antibiotics, resulting in healing of skin lesions with scarring.
9 citations
,
February 2013 in “Dermatologic clinics” This review examines therapeutic options for common pediatric skin conditions and reports promising results from immunotherapy, laser therapy, and bleach baths, but presents no new clinical findings.
9 citations
,
January 2004 in “Journal of dermatological treatment” This study reports that oral rifampicin effectively treated the pustular lesions of tufted hair folliculitis in a 47-year-old woman, with no relapses after one year.