research Pharmacological Inhibition of DGAT1 Induces Sebaceous Gland Atrophy in Mouse and Dog Skin While Overt Alopecia Is Restricted to the Mouse
Blocking DGAT1 reduces oil gland size in mice and dogs, but only mice experience hair loss.
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research A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels
The conclusion is that a new test was created to find substances that affect specific ion channels, and it works well for drug discovery.
research Bullous/Mucous Membrane
High blood pressure drugs often cause skin lupus, stopping the drug usually helps. A vaccine helps prevent genital herpes and HPV-16. More frequent light therapy clears psoriasis faster. No link was found between low iron and chronic hair loss.
research Psoriasis, Acne, and Disorders of Keratinization
Treating psoriasis with UVB light three times a week is faster than twice a week, and certain medications and lifestyle factors affect psoriasis treatment outcomes.
research Immunology
Blood pressure drugs can cause skin lupus, early treatment is key for baby herpes and diabetic foot ulcers, a certain vaccine works against genital herpes and HPV in women, more frequent light therapy helps psoriasis, smoking and drinking can worsen psoriasis, a cream clears up a type of skin cancer, and low iron levels don't cause chronic hair loss.
research Picogram Determination of Finasteride in Human Plasma and Semen by High-Performance Liquid Chromatography with Atmospheric-Pressure Chemical-Ionization Tandem Mass Spectrometry
Method detects finasteride in plasma and semen with high sensitivity and accuracy.
research A Medicinal and Edible Formula YH0618 Ameliorates the Toxicity Induced by Doxorubicin via Regulating the Expression of Bax/Bcl-2 and FOXO4
The formula YH0618 can reduce the harmful side effects of the chemotherapy drug Doxorubicin and protect healthy cells.
research Mechanistic Analysis of Human Skin Distribution and Follicular Targeting of Adapalene-Loaded Biodegradable Nanospheres With Insight Into Hydrogel Matrix Influence, In Vitro Skin Irritation, and In Vivo Tolerability
Researchers developed a nanomedicine for acne treatment that delivers medication with less irritation and is non-irritating for oily skin.
research Bioactive Compounds from the Roots of Asiasarum Heterotropoides
Two compounds from Asiasarum heterotropoides roots show potential as lung cancer treatments without harming normal cells.
research Shortness of Breath: An Uncommon Side-Effect of Cyproterone Acetate in the Treatment of Androgenetic Alopecia
Cyproterone acetate can cause rare shortness of breath in women.
research Nanoporous Silica Entrapped Lipid-Drug Complexes for the Solubilization and Absorption Enhancement of Poorly Soluble Drugs
Nanoporous silica entrapped lipid-drug complexes significantly improve the solubility and absorption of drugs that don't dissolve well in water.
research ICG Laser Therapy of Acne Vulgaris
Near-infrared laser therapy with Indocyanine Green dye improves acne by reducing inflammation without side effects.
research Promotion of Hair Growth by Rosmarinus Officinalis Leaf Extract
Rosemary leaf extract may be an effective natural treatment for hair growth and male pattern baldness.
research Treatment of Male Androgenetic Alopecia with Topical Products Containing Serenoa Repens Extract
Serenoa repens extract in topical products improves hair growth and appearance in male pattern baldness with mild side-effects.
research Caffeine Content in Newborn Hair Correlates with Maternal Dietary Intake
Newborns' hair shows how much caffeine their mothers drank during pregnancy.
research The Biology and Clinical Application of Systemic Glucocorticoids
Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.
research British Menopause Society Tools for Clinicians: Testosterone Replacement in Menopause
Testosterone replacement can help menopausal women with various symptoms, but should be used carefully and is not yet officially licensed in the UK for women.
research Nitric Oxide-Releasing Topical Therapeutic Agent for Atopic Dermatitis
SB414 may be an effective treatment for atopic dermatitis by reducing swelling and bacterial infection.
research Hormonal Contraceptives: Pharmacology Tailored to Women's Health
New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.
research Efficacy of Bergamot: From Anti-Inflammatory and Anti-Oxidative Mechanisms to Clinical Applications as a Preventive Agent for Cardiovascular Morbidity, Skin Diseases, and Mood Alterations
Bergamot may improve heart health, skin conditions, and mood, but more research is needed to confirm these benefits.
research LabeledIn: Cataloging Labeled Indications for Human Drugs
Researchers created LabeledIn, a detailed list of drug uses, showing the importance of human input in making such lists.
research Estimating the Contribution of the Prostate to Blood Dihydrotestosterone
The normal human prostate does not significantly affect blood DHT levels.
research A Review of Hedgehog Inhibitors Sonidegib and Vismodegib for Treatment of Advanced Basal Cell Carcinoma
Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.
research Liposuction and Tumescent Surgery
Tumescent liposuction is safe and effective for different cosmetic surgeries if done within recommended limits.
research Safety and Tolerability of the Dual 5-Alpha Reductase Inhibitor Dutasteride in the Treatment of Androgenetic Alopecia
Dutasteride is safe and effective for treating hair loss, but may decrease libido.
research High-Performance Liquid Chromatographic Method for the Determination of Finasteride in Human Plasma at Therapeutic Doses
Reliable method detects finasteride in human plasma at low doses.
research Trastuzumab Induced Chemobrain, Atorvastatin Rescued Chemobrain with Enhanced Anticancer Effect and without Hair Loss Side Effect
Atorvastatin reversed memory problems caused by cancer drug trastuzumab and improved its cancer-fighting abilities without causing hair loss.
research Addisonian Crisis in a Young Man with Atypical Anorexia Nervosa
A young man with an eating disorder had a life-threatening adrenal crisis due to an autoimmune condition, highlighting the need for better education on managing hormone treatments.
research Development of Finasteride Polymer Microspheres for Systemic Application in Androgenic Alopecia
Finasteride microspheres help reduce hair loss for up to eight weeks with fewer side effects.
research Renal Vitamins
Dialysis patients benefit from water-soluble vitamins but need careful management to avoid risks.