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The research observed that 40-nm self-assembled nanoparticles enhanced minoxidil penetration in hairy guinea pig skin compared to 130-nm nanoparticles, but this size effect was absent in hairless skin.

This announcement from Redfield Corporation introduces the first disposable linear slot punches for hair restoration surgery, with sharpness guaranteed for up to 500 recipient sites.

In this study, researchers developed a new microneedle patch delivery system for minoxidil, which enhanced its controlled release and improved hair growth in mice, potentially offering better treatment outcomes for androgenetic alopecia.

This review summarizes recent progress in microneedle-based drug delivery systems and discusses their potential impact on cellular mechanisms and immunization signaling pathways, highlighting the need for further development in fabrication methods.

This study found that a hair tonic combining fragrant pandan and celery extracts increased hair length in guinea pigs, with the 1:5 concentration showing the best growth activity.

This review explores the potential, challenges, and recent advancements of dissolving microneedles in drug delivery, summarizing their varied applications and current limitations without providing new clinical results.

This study found that Acanthus ebracteatus extract may promote the proliferation of human hair follicle dermal papilla cells and reported that its microemulsion was stable for 12 weeks.

Minoxidil sulfate, delivered through iontophoresis, can be used to treat hair loss.

This study focused on developing a nanoemulsion-based gel for delivering minoxidil, aiming to enhance its contact time with the scalp and potentially improve skin absorption compared to conventional topical solutions.

This study evaluated an in vitro inhalation method to assess the toxicological impacts of aerosols from heated hair products, revealing significant differences in cellular stress and IL-8 release among different test materials, which may help in developing safer products.

This study found that POD-loaded solid lipid nanoparticles using 0.5% poloxamer 188 and 1.5% soybean lecithin (P-SLN) improved epidermal targeting and POD accumulation in porcine skin compared to traditional tincture.

This review discusses recent advances in skin penetration mechanisms, specifically focusing on the enhanced understanding of the follicular pathway and its implications for transdermal therapies, immune system targeting, and nanoparticle safety.

This paper evaluates the therapeutic response of androgenetic alopecia to topical application of specific compounds using digital drug delivery but reports no new clinical results.

This review examines microneedle patches for drug delivery, detailing their designs, materials, manufacturing methods, and potential advantages, but reports no new clinical results.

This review discusses iontophoresis, low-frequency ultrasound, and microneedles for enhancing topical drug delivery in dermatological treatments and reports no clinical results; it emphasizes their mechanisms and potential uses.

In this study, researchers developed a dissolvable microneedle patch combining HA-TEMPO and Portulaca oleracea L.-derived nanoparticles, which effectively reduced oxidative stress and inflammation in an atopic dermatitis model while restoring immune balance, suggesting a promising treatment strategy.

This study found that microneedle delivery of Polygonum multiflorum extract led to earlier pigmentation and hair regrowth in mice with androgenetic alopecia.

The researchers reported that a novel leave-on treatment containing caffeine, niacinamide, panthenol, dimethicone, and an acrylate polymer significantly increased the diameter and improved the mechanical properties of scalp hair fibers, suggesting it may help mitigate thinning hair.

This study introduces a co-design framework using finite element analysis to optimize separable bubble microneedles, demonstrating enhanced transdermal and sublingual drug delivery in preclinical models. In vivo results showed faster hair regrowth and glucose lowering in animals, indicating potential improvements over traditional methods.

This study found that an anhydrous gel formulation containing sertaconazole nitrate effectively penetrated the stratum corneum for treating fungal infections without causing irritation.

Smart microneedles improve hair loss treatment by delivering drugs precisely with fewer side effects.

A new method was developed to detect pesticide residues on apples without damage.

This study demonstrates that pea sprout extract promotes hair growth by activating specific signaling pathways and providing antioxidant and anti-inflammatory effects, suggesting its potential as a natural alopecia treatment.