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Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

The Rotterdam Study aims to understand various diseases in older adults.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Melatonin may benefit skin health and could be a promising treatment in dermatology.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

Stem cell niches support, regulate, and coordinate stem cell functions.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Matriptase is crucial for keeping epithelial tissues healthy and functioning properly.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Stress can stop hair growth in mice, and treatments can reverse this effect.