349 citations,
January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
143 citations,
September 2008 in “Experimental gerontology” Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
132 citations,
January 2017 in “International Journal of Molecular Sciences” Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.
22 citations,
September 2018 in “Medical Clinics of North America” Facial aging is caused by natural processes and external factors, and can be managed with preventative measures and a variety of treatments tailored to individual needs.
10 citations,
November 2022 in “Protein & Cell” Quercetin significantly helps hair growth by activating hair follicles and improving blood vessel formation around them.
6 citations,
October 2022 in “Journal of cell science” Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.
6 citations,
June 2021 in “Developmental biology” Dermal EZH2 controls skin cell development and hair growth in mice.
1 citations,
August 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The research created a detailed map of skin cells, showing that certain cells in basal cell carcinoma may come from hair follicles and could help the cancer grow.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The mTurq2-Col4a1 mouse model shows that cells can divide while attached to stable basement membranes during development.
February 2023 in “Research Square (Research Square)” Blocking IL-17 can reduce skin inflammation in a mouse model of pityriasis rubra pilaris.
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Ezh2 controls skin development by balancing signals for dermal and epidermal growth.
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Dermal EZH2 controls skin cell growth and differentiation in mice.
January 2018 in “Stem cell biology and regenerative medicine” ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.
61 citations,
June 2022 in “Journal of Controlled Release” Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
11 citations,
March 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” A specific group of skin stem cells was found to help maintain hair follicle cells.
2 citations,
December 2023 in “International journal of molecular sciences” Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.
December 2023 in “The journal of cell biology/The Journal of cell biology” The mTurq2-Col4a1 mouse model shows how the basement membrane develops in live mammals.
9 citations,
November 2018 in “Journal of cosmetic dermatology” Orobanche rapum extract rejuvenates skin and protects skin bacteria, leading to healthier skin.
156 citations,
August 2016 in “Journal of controlled release” Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.
1 citations,
January 2012 in “Elsevier eBooks” The document concludes that the skin is a complex organ providing protection, sensation, and healing, with challenges in treating conditions like itchiness.
March 2015 in “Plastic and reconstructive surgery” Human skin has multiple layers and functions, with key roles in protection, temperature control, and appearance.
19 citations,
February 2018 in “Nutrients” Certain zinc transporters are essential for healthy skin and managing zinc in the body could help treat skin problems.
277 citations,
July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
144 citations,
September 2006 in “Clinics in Dermatology” Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.
113 citations,
December 2000 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” KGF and activin are crucial for skin healing and repair.
January 2018 in “Stem cell biology and regenerative medicine” The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.
January 1997 in “Elsevier eBooks” Hair and nails are skin parts that develop early and serve protective and functional roles.
6 citations,
January 2009 in “Elsevier eBooks” The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.
426 citations,
August 2014 in “Nature Medicine” Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.
10 citations,
September 2022 in “Journal of Biophotonics” Blue light therapy is safe for skin and may protect against UV radiation.