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This review discusses the developments over the past five years in nanozyme-based theranostics for tumor therapy, including their classification, design, and synergistic strategies. It also outlines the challenges and prospects of using nanozymes to enhance selectivity, biosafety, repeatability, and stability in therapeutic applications.

This review addresses the effects of testosterone on brain development and examines both the established sex differences in brain functions and the debate surrounding structural dimorphism in neuropsychiatric conditions.

This study found that mutations in the TULP3 gene are associated with progressive degeneration of the liver, kidney, and heart in adults, highlighting the importance of early detection and management.

This article contains the late-breaking abstracts from the 39th Annual Conference of the American Society for Laser Medicine and Surgery and does not present new research results.

This study found that the human hairline is closely linked to several cranial, cerebral, and vascular structures, enabling precise localization of key neuroanatomical landmarks, which could assist in planning neurosurgical procedures.

This study highlights that while advances in dermatology, such as biologics and JAK inhibitors, have improved treatments for conditions like atopic dermatitis and psoriasis, challenges remain, including issues with lasting efficacy and the need for more personalized therapies.

This review highlights how single-cell transcriptomics has advanced understanding of tissue regeneration by revealing cellular diversity and key molecular interactions in animal models, despite methodological challenges, suggesting future applications in developing targeted regenerative therapies.

In this study, researchers identified six novel prognostic biomarkers for bladder cancer and developed a predictive model that effectively stratifies patients into high-risk and low-risk groups based on immune cell infiltration differences and gene expression.

This study developed a model for detecting sparse hair clusters using enhanced object detection neural networks and medical images, which accurately identifies and counts sparse hair clusters with greater accuracy and efficiency than existing methods.

This review covers red light Transcranial LED therapy for hippocampal memory impairment in aging and Alzheimer's but reports no clinical results, highlighting a need for further research into its mechanisms and effects.

This study found that epidermal stem cells in live mice exhibit coordinated intercellular Ca 2+ signaling governed by G2 cycling stem cells and mediated by Connexin43, essential for tissue-wide communication during regeneration.

This review discusses the complex effects of testosterone on the brain, emphasizing sex differences, and reports no clinical results; the authors highlight the inconsistencies in current study findings.

This study found that in male rat hippocampal slices, DHT is necessary for low frequency stimulation-induced long-term depression, while E2 synthesis is essential for high frequency stimulation-induced long-term potentiation.

This study observed that a CARASIL mouse model demonstrated abnormal behavior, vascular and cellular changes, and upregulation of the TGF-β/Smad signaling pathway, indicating its potential involvement in CARASIL pathogenesis.

This review investigates how the chirality of peptides affects their ability to form hydrogels, comparing the structural and mechanical properties of hydrogels made from homochiral and heterochiral peptides, and discussing their potential biological applications.

In this scoping review, researchers observed that while AI-assisted trichoscopy holds promise for standardized assessments of hair and scalp disorders, its clinical translation is limited by small proprietary datasets, inconsistent validation protocols, and a scarcity of real-world clinical studies.

This review highlights advancements in nanotechnology-based treatments for androgenetic alopecia, noting that these strategies could improve targeting and modulation of hair follicle environments compared to traditional therapies like minoxidil and finasteride, but also emphasizes challenges around safety, manufacturing, and regulation.

This study reported a new method enabling the observation of the full leg regeneration process in the crustacean *Parhyale hawaiensis* over 10 days, capturing cellular resolution while minimizing photodamage, through innovative imaging techniques and computer-assisted cell tracking.

This study found that corticosterone promotes neurosteroid synthesis in hippocampal neurons, which can lead to ethanol-mediated synaptic dysfunction even at moderate ethanol levels, potentially contributing to stress-related cognitive impairment from alcohol.

This study found that celery supplementation improved cognition and behavioral disorders in LPS-exposed mouse offspring by increasing levels of dopamine, acetylcholinesterase, and serotonin in the forebrain.

This study found that both declining levels of the neurosteroid THP and increasing levels of estradiol before puberty trigger maximal expression of α4βδ GABAA receptors in the CA1 hippocampus of female mice.

In this study, researchers found that coordinated intercellular Ca2+ signaling among basal stem cells in mice is crucial for cell cycle progression and tissue-wide communication during epidermal regeneration.

This review highlights that gut dysbiosis and bacterial extracellular vesicles are key factors in PCOS pathophysiology, and suggests AI-driven analysis of these profiles could enhance diagnostic accuracy and treatment personalization, though ethical concerns like data privacy and bias must be considered.

This study developed a 3D bioprinted skin model to mimic pemphigus vulgaris, providing a tool to study disease mechanisms and test targeted therapies by reproducing the architecture and pathogenic disruptions of native skin.

Photocrosslinkable biomaterials can improve wound healing by controlling mechanical environments.

This review suggests that hyperspectral and terahertz imaging show promise in non-invasively assessing scalp changes associated with hair loss, but further validation is needed for clinical application.

This review explores recent advancements in skin tissue engineering using 3D bioprinting, discussing current methods, bioink formulations, and outlining both achievements and limitations without presenting new clinical results.

This study reported that the PM-DBiGRU model enhances aspect-level sentiment classification in drug reviews, outperforming existing methods on the newly proposed SentiDrugs dataset.

This study found that young women with PCOS exhibited altered white matter microstructure and reduced cognitive performance compared to matched controls.

This study found that dental students' manual dexterity was weakly associated with their performance in skills-based assessments, while self-perceived skill levels showed no significant correlation with assessment outcomes, suggesting a potential benefit from focusing on dexterity enhancement in dental education.