10 citations,
May 2012 in “PloS one” Low ERCC3 gene activity is linked to non-pigmented hair growth.
12 citations,
February 2019 in “Skin research and technology” White hair has less lipid content and absorbs water differently than brown hair.
21 citations,
April 1990 in “Journal of comparative neurology” The study found that nerve signals are stronger when there are more connection points, but not necessarily denser, along the nerve's path in the spine.
21 citations,
March 2017 in “Skin research and technology” Removing external lipids from hair reduces moisture and increases strength, while removing internal lipids decreases water permeability.
ILC1-like cells may contribute to hair loss in alopecia areata.
ILC1-like cells may contribute to hair loss in alopecia areata and could be new treatment targets.
48 citations,
May 1991 in “The journal of investigative dermatology/Journal of investigative dermatology” Trichohyalin is also found in the outer layers of normal human skin.
4 citations,
November 2004 in “Clinical and Experimental Dermatology” Hair length and thickness are related, with thickness peaking at about a quarter of the hair's maximum length.
39 citations,
May 2010 in “Stem Cells” Ephrins slow down skin and hair follicle cell growth.
20 citations,
July 2008 in “Dermatologic Therapy” The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.
13 citations,
March 2019 in “Journal of cosmetic dermatology” Heat damages hair, with Asian hair losing more protein than Caucasian hair.
7 citations,
March 2019 in “Journal of cosmetic dermatology” African hair has the most lipids, while Caucasian hair is more hydrated and stronger.
Hair loss in African American women, caused by hair care, genetics, and environment, needs more research for better treatment.
330 citations,
December 2009 in “Cell stem cell” SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.
320 citations,
December 2018 in “Frontiers in Immunology” Changing how mesenchymal stromal cells are grown can improve their healing abilities.
291 citations,
April 2010 in “Gastroenterology” Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.
205 citations,
March 2012 in “Science Translational Medicine” PGD2 stops hair growth and is higher in bald men with AGA.
150 citations,
October 2010 in “The American Journal of Pathology” The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
150 citations,
April 1999 in “Dermatologic Clinics” Laser hair removal effectiveness depends on targeting hair structures without harming the skin, and improvements require more research and expert collaboration.
145 citations,
November 2018 in “Nature Communications” The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
131 citations,
July 2009 in “Experimental Dermatology” The document concludes that specific cells are essential for hair growth and more research is needed to understand how to maintain their hair-inducing properties.
97 citations,
March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
96 citations,
April 2007 in “Journal of Investigative Dermatology” Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.
88 citations,
July 2019 in “International Journal of Molecular Sciences” Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.
73 citations,
November 2005 in “Journal of Investigative Dermatology Symposium Proceedings” Some women with common hair loss may develop permanent hair loss.
54 citations,
April 2019 in “Journal of cellular physiology” miR-218-5p helps skin and hair growth by targeting SFRP2 and activating a specific signaling pathway.
51 citations,
September 2020 in “Cell Metabolism” Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.
41 citations,
January 2020 in “BioMed Research International” Micrografts improve hair density and thickness without side effects.
35 citations,
May 2021 in “Nature communications” The skin's basement membrane has specialized structures and molecules for different tissue interactions, important for hair growth and attachment.
30 citations,
November 2018 in “EMBO Reports” The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.