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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Four-amino acid part makes enzyme sensitive to finasteride.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Mushrooms have beneficial properties for skin and hair care products and have great potential for future cosmetic use.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

Both mouse and rat models are effective for testing alopecia areata treatments.

Testosterone may slow down wound healing and increase inflammation.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Photobiomodulation may help with hair growth and wound healing, but research is inconsistent and needs better quality studies.

Dermatologists need to know about cosmetics to help patients with skin issues and recommend safe products.

St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Where melanoma is on the body affects survival chances; melanomas on the back of the head are worse, while those on thighs and arms are less severe, and more sun exposure might improve survival.

Annurca apple supplement safely increases hair growth and keratin in humans.

Commercial hair loss websites promote Propecia by making men feel insecure about baldness and suggesting it's a medical issue needing treatment.

Dental erosion is common in adolescents and is linked to diet and higher socioeconomic status.

Genetic variants linked to ten skin diseases were found, showing both immune and non-immune factors play a role.

The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.