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This study found that the uptake of molecules by hair is influenced by both hydrophobic and ionic charge interactions, with binding affinity decreasing as pH approaches the solute's dissociation constant.

This study concluded that albumin-bound testosterone is biologically important and significantly contributes to testosterone bioavailability in women receiving spironolactone.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

This study found no evidence of androgen deficiency or decreased peripheral androgen action in men with persistent sexual symptoms after finasteride use, but identified links to depressed mood and abnormal brain function.

This review discusses advancements in the use of microneedle arrays and nanoparticles for transdermal delivery of therapeutics, noting challenges in overcoming the skin barrier and summarizing recent clinical trial achievements in areas like cancer therapy and gene therapy.

This review discusses the role of reactive oxygen species in regulating oscillating apoplastic pH gradients and growth in plant root hairs and pollen tubes, reporting no new experimental results.

This review discusses the potential roles of calcium in the regulation of pluripotent and tissue-specific stem cells but reports no new experimental results, highlighting areas for future research.

This study found that polymeric nanoparticles retained more minoxidil and facilitated superior drug permeation compared to lipid nanoparticles, although premature drug release affected formulation performance.

This study developed a high performance capillary electrophoresis method, validated for both legal and illicit minoxidil-based products, to confirm minoxidil's presence alongside known impurities.

This study found that alkali bromide solutions are absorbed into hair depending on salt activity, and the presence of the salt increases water absorption compared to normal conditions.

This case report documents the first successful management of accidental minoxidil toxicosis in a dog, resulting in full recovery after treatment with supportive care, including medications for blood pressure and potential toxicity mitigation.

This study analyzed the geometric and electronic properties of baicalin conformers, finding that BCLa2TT and BCLa1TT conformers exhibit high stability in aqueous solutions and are favorable for interactions with positively charged species.

Among families with pediatric brain disease, this study identified over 200 novel genetic causes, revealing potential treatment points using drug repurposing or nutritional supplementation.

This study investigated the integration of crystal engineering and microneedle technology for androgenetic alopecia treatment, finding that microneedles loaded with newly developed Kopexil multicomponent crystals reduced drug diffusion rates in vitro compared to standard formulations.

This study found that vimentin is essential for proper wound healing and cell growth by influencing EMT signaling and mTOR activity in mice.

This study identified key genes and pathways involved in the growth and development of forest musk deer hair follicles, providing insights into molecular regulation and laying groundwork for future research on related diseases.

This study demonstrated that cryogelation of human hair keratin allows the development of 3D scaffolds with tunable properties, supporting cell adhesion and proliferation for potential biomedical applications.

This Ph.D. project aims to evaluate the self-assembling potential of hair keratin extracts and study the cellular response to both crude and purified keratins, highlighting their potential applications from biomedical to water remediation.

This chapter reviews the use of liposomes and cyclodextrins to improve the delivery and effectiveness of the peptide angiotensin-(1-7) in various therapeutic applications and reports no new experimental results.

This research found that androgen bioactivity plays a role in normal female sexual differentiation, suggesting females develop within a significant androgenic environment, with implications for understanding conditions like congenital adrenal hyperplasia.

This article discusses the influence of estrogens on hair follicle growth and metabolism, suggesting a significant role alongside androgens in hair growth control but reports no new clinical results.

This study reviews the evolution and modifications of microneedle drug delivery systems, initially designed for percutaneous use, now expanded for targeting a variety of tissues and organs such as ocular, oral mucosal, and gastrointestinal, suggesting widespread future applicability.

This review discusses the developments over the past five years in nanozyme-based theranostics for tumor therapy, including their classification, design, and synergistic strategies. It also outlines the challenges and prospects of using nanozymes to enhance selectivity, biosafety, repeatability, and stability in therapeutic applications.

This review discusses various substances that can impact male fertility and stresses that products should be confirmed 'sperm-safe' through rigorous testing, not assumptions; it reports no new study results.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

This article discusses how drug molecules integrate into hair fibers, focusing on biological transport mechanisms and physicochemical factors, but reports no new experimental findings.

This article contains additional supporting information available online but presents no new research findings.

Finasteride may help reduce symptoms in male Tourette syndrome patients.

The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.

This review explores the use of skin penetration enhancers like Transcutol® in various formulation systems, discussing their mechanisms and effectiveness in improving transdermal drug delivery without breaching the skin.