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Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

HLA-DRB5 and other genes may be linked to alopecia universalis.

Activating Nrf2 can help protect against hearing loss.

Genetically variant peptides are reliable for forensic identification despite age-related changes in hair proteins.

Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.

A specific gene variant causes severe skin issues and increases infection risk, requiring careful medical monitoring.

Oxidative stress plays a significant role in alopecia areata, and new treatments may include JAK inhibitors and antioxidants.

Leptin, a hormone from fat cells, affects immune responses and can influence skin diseases and hair growth.

Sox6 is important in heart and kidney health, affecting diseases like diabetes, heart disease, and high blood pressure.

EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.

LIPH mutations in Japan cause varying degrees of hair loss and woolly hair.

Metformin works better for adolescent girls with PCOS who have certain genetic variations.

Basonuclin 2 is vital for the development of facial bones, hair follicles, and male germ cells in adult mice, and its absence can lead to dwarfism and abnormal follicles.

Vitamin D is important for skin health, but more research is needed to understand its full effects and treatment potential.

The genes KRT25 and SP6 affect curly hair in horses, with KRT25 also causing hair loss. If both genes are mutated, the horse gets curly hair and hair loss. KRT25 can hide the effect of SP6.

Researchers identified a new variant of the FGF5 gene in sheep that affects hair length.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

Sheep and goat hair fibers are complex due to keratin-associated proteins, which are important for fiber properties and growth.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

Women with PCOS have more Bifidobacterium in their gut compared to those without PCOS.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

Allopregnanolone changes gene expression in glioblastoma cells.

The rhg mutation in mice affects the Oat gene, causing hair growth issues and other symptoms.

Some children in Malaysia with symptoms have either profound or partial biotinidase deficiency, and early testing and treatment are important.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

Adult mice with CBS deficiency show minimal health issues and normal lifespan despite high homocysteine levels.

The research found specific genes that may cause longer hair in Tianzhu White Yak.

The KRTAP21-1 gene affects wool yield and can help improve wool production.

Forensic DNA phenotyping can help generate new leads in cold cases but faces accuracy, legal, and acceptance challenges.

The study found that genetic differences related to hair growth and other traits help cashmere goats adapt to high-altitude environments.