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In this study, researchers found that hTERT/SV40 immortalization of human dermal fibroblasts up-regulates skin cell markers and highlights the SIRT1 and miR-93 pathways' roles in maintaining fibroblast proliferation, potentially benefiting developments in the cosmetic industry.

This study found that precision 40Hz gamma-transcranial alternating current stimulation significantly improved negative and cognitive symptoms in patients with schizophrenia compared to a sham group, suggesting promising potential for this neuromodulation technique in treating these symptoms.

This study introduces a customizable 3D-printed microscope stage insert for inverted confocal microscopes, improving accessibility and usability of intravital microscopy for observing cell dynamics in live mice.

This article discusses how recent research suggests that aggressive video games have little effect on aggression and violence among players, calling for professional organizations to update their policy statements accordingly.

In this animal study, SM-215 treatment in male mice showed increased hair growth and decreased indicators of hair follicle damage and scalp inflammation, suggesting potential benefits for androgenetic alopecia.

This study introduced laser particles as a new imaging probe capable of real-time tracking of thousands of individual cells in 3D tumor models, suggesting potential for advanced single-cell analyses.

This study found a specific T cell receptor that may be key in carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis, suggesting potential therapeutic targets.

This study demonstrated that combining cell conditioning with mild protease digestion enhanced the visualization of versican mRNA in formalin-fixed mouse skin tissue sections compared to using either technique alone.

This study found that overexpression of Smad7 in transgenic mice led to severe alterations in multiple epithelial tissues, resulting in early death after birth.

This study found that using a contrast agent in Microbeam Radiation Therapy simulations increased the target dose but concluded that using a linear accelerator as an X-ray source did not preserve MRT advantages.

This review discusses recent advances in microfabrication and microfluidic technologies for improving the production of organoids and spheroids, but it reports no new experimental results.

This case report suggests that Trichostasis spinulosa should be considered in diagnosing treatment-resistant open comedone-like lesions and that skin surface biopsy might be an effective diagnostic method.

This study found that Quantitative Mass Spectrometry Imaging offers precise localization and quantification of active compounds in skin tissues, demonstrating benefits over traditional LC-MS in drug penetration studies.

This study developed ultrasound-responsive sutures that generate reactive oxygen species to kill bacteria without antibiotics, showing over 80% bacterial reduction and promoting healing in a rat model, though more validation is needed.

This review discusses synthetic piezoelectric polymers within the smart polymer family, detailing their applications in various medical fields, but reports no new experimental results.

This study identified a 14,883 bp genomic deletion affecting the Plcd1 and Vill genes as likely responsible for the abnormal phenotype observed in snthr-1Bao mice.

This study developed the TLMG hydrogel, a seamless in situ biointerface platform, demonstrating robust adhesion, high conductivity, and therapeutic effects for intelligent wound management in complex animal models and human tests, indicating its promise for integrated bioelectronic medicine.

This study found that selective androgen receptor modulators (SARMs) significantly inhibited tumor growth and metastasis-promoting factors in AR-positive triple-negative breast cancer models.

This case report examines a 10-year-old girl with Satoyoshi Syndrome, highlighting the challenges in diagnosing and managing this rare autoimmune disorder.

This study found that the film-trigger applicator system enhanced drug delivery efficiency and skin penetration of dissolving microneedles compared to traditional patch systems in both lab and animal models.

This review discusses the mechanism and side effects of smoothened inhibitors for advanced basal cell carcinoma, reporting no new clinical results and highlighting current management strategies for these adverse events.

This study found that scalp micropigmentation provided moderate to great improvement in scalp coverage and patient satisfaction for those with hair loss, with any adverse effects being mild and temporary.

This study found that scanning electron microscopy with argon sputter etching visualizes hair lipids at the cell membrane complex as distinctive convex structures, shedding light on their role and localization in human hair.

In this study, HPH-15, a newly synthesized compound, demonstrated potential in reducing skin fibrosis in a mouse model by targeting underlying pathogenic mechanisms and exhibited a good safety profile, warranting further clinical trials for fibrotic skin disorders like systemic sclerosis.

This study optimized a screening assay to identify molecules that inhibit or enhance TRPM5 ion channel activity, which may have implications for treating dysfunctions linked to cardiac arrhythmias and diabetes.

This study introduced a novel microscopy system using an Er3 + −doped femtosecond fiber laser, achieving detailed imaging of biological structures in plant and skin samples with improved spatial resolution for various applications, including in vivo imaging.

This article outlines a protocol for scanning electron microscopy of murine skin and primary keratinocyte monolayers, providing a guide for sample preparation and examination.

This study introduced a reproducible human model using 3D-SeboSkin technology to study hidradenitis suppurativa, allowing better maintenance of skin integrity and replication of biomarker expression patterns compared to traditional skin cultures, suggesting its value for further research.

This reprint reviews 14 papers on advances in solid-phase microextraction techniques for bioanalysis, reporting no new results.

This study found that S1PR1 signaling in mouse aortic endothelial cells varied by location and subtype, influencing inflammatory and lymphangiogenic gene expression through distinct molecular pathways.