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Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

Activating the Sonic hedgehog pathway can help regenerate hair follicles during wound healing in mice, potentially improving regeneration after injury.

Vinblastine and its metabolites may cause nausea and hair loss by binding to specific receptors and could lead to better chemotherapy drugs with fewer side effects.

Targeted therapy for skin cancer is complex due to the role of the hedgehog pathway in both cancer and hair growth.

The hedgehog signalling pathway is key in skin development and basal cell carcinoma, offering insights for prevention and treatment.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.

Using a gene therapy with the Sonic Hedgehog gene helps mice regrow hair faster after losing it from chemotherapy.

Sonidegib and vismodegib are similarly effective for advanced basal cell carcinoma, but sonidegib might have a slightly better safety profile.

Hedgehog signaling is crucial for mammary gland development over hair follicles.

Hes1 protein is important for hair growth and regeneration, and could be a potential treatment for hair loss.

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.

Cold atmospheric plasma may speed up wound healing and control infections.

Combining platelet-rich plasma injections and gel may effectively treat morphea, improving skin elasticity and reducing pain.

Wnt-signaling is regulated differently in skin cells and immune responses during wound healing.

The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.

Muscles and nerves that cause goosebumps also help control hair growth.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.

Mice without Vitamin D receptors have hair growth problems because of issues in the hedgehog signaling pathway.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Hair loss in cancer patients can be related to the cancer itself, treatment, or other conditions, and understanding it is important for diagnosis and patient care.

The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.

New treatments for advanced skin cancer are improving patient outcomes, but drug resistance and finding the right treatment combinations are still big challenges.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

Green tea compound EGCG helps mink hair follicles grow by affecting certain cell growth pathways.