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Biomedical engineers are crucial for developing better treatments for chronic and autoimmune diseases.

The document concludes that side effects from Smoothened inhibitor drugs for skin cancer are reversible and can be managed with a team approach to maintain quality of life.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.

Using a gene therapy with the Sonic Hedgehog gene helps mice regrow hair faster after losing it from chemotherapy.

Hedgehog signaling is crucial for mammary gland development over hair follicles.

New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.

Indian Hedgehog helps control skin cell growth and protects against aggressive skin cancer.

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

The research suggests new treatments for skin cancer could target specific cell growth pathways.

Environmental factors like smoking, UV exposure, and poor diet contribute to hair loss and graying, and lifestyle changes can help manage it.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Targeted cancer therapies often cause serious skin problems that need careful management.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

Shampoos are designed to clean and improve hair and scalp health, with specific ingredients for different hair types and conditions.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

The conclusion is to use scalp cooling, gentle hair care, and treatments like minoxidil for managing hair loss from chemotherapy, and stresses the need for more research and collaboration in this area.

New genes found linked to balding, may help develop future treatments.