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The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Nerves and chemicals in the body can affect hair growth and loss.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Environmental factors at different levels control hair stem cell activity, which could lead to new hair growth and alopecia treatments.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.

The document concludes that the effectiveness of platelet rich plasma in aesthetic surgery is unclear due to inconsistent reporting and lack of objective measures in studies.

Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.

Eclipta alba has many health benefits and contains compounds with potential for drug development.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Live imaging has advanced our understanding of stem cell behavior and raised new research questions.

Trichoscopy is useful for diagnosing and monitoring systemic lupus erythematosus, with certain hair and scalp changes indicating more active disease.

Cashmere and milk goats have different hair growth cycles and gene expressions, which could help improve wool production.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Some plants with flavonoids may help treat hair loss and promote hair growth.

Minoxidil treatment increases aorta elasticity and reduces stiffness in aged mice, potentially helping with age-related heart issues.