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This study demonstrated that both classical and atypical BSE strains from cattle can be transmitted to goats, highlighting the importance of surveillance in protecting public health.

Small molecule DMF improves psoriasis and multiple sclerosis, adult skin cells can be made to grow new hair, certain skin cells initiate hair growth, IL-17C controls gut health and can cause skin inflammation, and skin cells produce IL-17 that can lead to psoriasis.

This study found that while yak belly hair is chemically similar to human hair, its higher porosity and lower mechanical strength limit its usefulness as a substitute in hair dye development.

This review discusses the potential of exosomes as a therapy for hair loss and the need for better regulation and understanding of their molecular effects, but reports no new clinical results.

This study identified a small molecule that activates GLI1, suppressing neuroblastoma cell growth, which may aid in developing new treatments for high-risk neuroblastoma cases.

This study suggests that exosomes derived from mesenchymal stem cells may promote hair growth and improve skin health by enhancing dermal papilla cell proliferation and modulating inflammation and oxidative stress.

The researchers reported that topical application of small-molecule Wnt inhibitors significantly reduced fibrosis and promoted regenerative wound healing in mice.

This review discusses the development and potential therapeutic effects of nitroxide small molecule agents for age-related macular degeneration and cardiovascular disease, but reports no new clinical results.

This study found that the small molecule honokiol may protect against inflammation, collagen breakdown, and cell damage caused by cigarette smoke in skin cells cultured in vitro.

This study suggests that five small molecules can induce hair follicle neural crest stem cells to differentiate toward motor neuron progenitor cells with a unipotent differentiation potential.

This study found that the CXXC5 protein is overexpressed in diabetic foot ulcer tissues, suppressing wound healing, and that the small molecule KY19334 accelerated healing in diabetic mice by activating the Wnt/β-catenin pathway.

This study found that KY19382, a small molecule activating the Wnt/β-catenin pathway, significantly improved wound healing by enhancing cell migration, increasing collagen and stem cell markers, and accelerating re-epithelialization and neo-epidermis formation in a murine model without causing significant cytotoxicity.

Exosomes might help hair regrow, but more human testing is needed.

This article discusses the development and clinical progress of PROTAC technology, particularly focusing on the New Drug Application for vepdegestrant, an estrogen receptor-targeting PROTAC, marking significant advancements in targeted protein degradation therapies.

In this study, small molecule-loaded silk fibroin nanofiber scaffolds with chitosan achieved sustained release of GSK-3 inhibitor SB216763, leading to enhanced wound healing and hair follicle neogenesis in skin regeneration efforts.

This review highlights that exosomes from adipose-derived stem cells, particularly those enriched with circ-Ash1l, can inhibit ferroptosis and reduce UVB-induced skin aging by delivering GPX4-promoting signals to damaged cells, thus offering a potential regenerative therapy for photoaged skin.

This review discusses recent advancements in cutaneous drug delivery technologies and the potential of transfollicular pathways for improved treatment of skin conditions, but reports no clinical results.

This review discusses the diagnostic challenges of androgen and estrogen-secreting adrenal tumors and highlights that the presence of metastases is the most reliable indicator of malignancy; it reports no new clinical findings.

This study found that small amounts of RNA present in horsehair roots can be used for molecular biological analysis, although detecting mRNA transcripts in the hair shaft is more challenging.

This study found that primary stem cells from concentrated growth factor can differentiate into adipogenic, endothelial, and neuronal lineages in vitro, suggesting potential for use in regenerative therapies.

This review reports that oral collagen peptide supplements may improve skin elasticity, hydration, and wrinkle appearance while also supporting hair and nail health and wound healing, but emphasizes the need for longer, high-quality studies due to current research limitations and variability in findings.

In this case study, a nine-year-old boy with alopecia universalis following severe chickenpox showed complete hair regrowth after treatment with tofacitinib, suggesting the drug's potential in managing varicella-zoster virus-induced alopecia by modulating immune responses.

This article reviews the cutaneous reactions and characteristic skin changes associated with chemotherapy, radiation therapy, and new targeted cancer treatments, reporting no new clinical results.

This review explores the complex factors involved in alopecia areata, such as immune and genetic influences, and discusses advances in diagnostic and therapeutic approaches, while reporting no new clinical results.

This study found significant racial and ethnic disparities in the incidence and psychological impact of chemotherapy-related alopecia, with Asian women experiencing the greatest burden, highlighting the need for personalized and culturally sensitive care.

This study develops FR-1, a topical small molecule, which reduces scarring and avoids skin atrophy in a murine wound model, showing potential for treating fibrosis without the side effects of current therapies.

This study found that certain T cell-associated genes were upregulated in dogs with Vogt-Koyanagi-Harada syndrome and vitiligo, suggesting a shared immunopathogenesis with humans.

This article proposes a strategy for identifying bioactive, small molecule, metallo-species in Traditional Chinese Medicine to explore their potential for drug development, but reports no new results.

This review highlights the potential of peptide-based PROTACs (pPROTACs) in expanding the target range of protein degraders beyond small-molecule limitations, particularly for undruggable proteins, by utilizing advances in design, conjugation, and bioPROTAC technology.

In this ex vivo study, inhibiting Ezh2 with a small molecule slowed human hair growth by decreasing proliferation and increasing apoptosis in the outer root sheath.