Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the early phases of melanomagenesis and the factors influencing melanoma cell variability and reports no new clinical results.

This article reviews the variations and risks associated with skin conditions in melanin-rich individuals, including assessment challenges and complications from common skin treatments, but presents no new research findings.

This study found that female Holdobaggy goslings have higher melanin content in their dorsal plumage than males, suggesting that initial plumage color can be used for sex identification.

This review examined and discussed the role of dermis-derived factors in the regulation of melanogenesis, noting their significance in both normal and abnormal mammalian skin conditions, suggesting an underexplored area of study compared to dermal and epidermal influences.

The authors observed that the patterned melanoderma on the hairless scalp of fair-skinned Caucasian men with androgenic alopecia resembled similar patterns seen on facial skin.

This review discusses the mechanisms of laser and IPL hair removal, particularly for darker skin types, and reports no new findings, highlighting potential adverse effects like pigmentation changes or scarring with improper use.

This review highlights the benefits of long-pulsed Nd:YAG lasers for hair removal in individuals with Fitzpatrick skin types IV-VI, offering deeper follicular targeting with reduced melanin interaction, and examines emerging technologies like radiofrequency and RF microneedling for safe treatment options in skin of color.

This study found that splenic melanosis in C57BL/6 mice is associated with synchronized skin melanization during hair cycles, but decreases with age.

This study found that inhibiting PKC-β activity with bisindolylmaleimide reduces pigmentation in the skin and hair of guinea pigs and mice by preventing tyrosinase activation.

This study investigated the use of dissolving microneedle patches to improve the skin-lightening effects of alpha-arbutin and resveratrol, finding that the patches enhanced intradermal delivery and slightly decreased the melanin index without affecting skin hydration or causing irritation over 24 hours.

This study investigated the genetic basis of coat color variation in cattle using skin transcriptome and whole-genome analyses, identifying the ASIP gene as a significant determinant that is differentially expressed and under strong positive selection in black and brown cattle breeds.

This study found that collagen oligopeptides from puffer skin may reduce skin melanin and increase hydroxyproline content in guinea pigs, suggesting potential skin whitening and anti-aging effects.

This review examines various skin pigmentation disorders, their causes, and potential treatments, detailing 25 plants, 4 marine species, and 17 clinically tested topical and oral medications for managing these conditions.

This study found that transgenic mice overexpressing HGF/SF are more susceptible to UVA-induced melanoma, with melanin in the papillary dermis interacting with UVA to induce melanoma.

This review summarizes the biological process of melanogenesis and evaluates natural skin-whitening treatments based on their mechanisms affecting melanin production, aiming to inform on the effects and awareness of skin-bleaching creams.

Some chemicals can permanently or temporarily remove color from skin and hair, which can be distressing and is not well-regulated in cosmetics.

This review examines the evolution of human skin pigmentation and its genetic basis, suggesting that variations might be due to a few interacting gene pairs, and reports no new research findings.

This study found that variations in mouse skin thickness, influenced by gender and hair growth cycles, significantly affect optical scattering measurements, which are important for developing biomedical optics techniques.

This article reviews the steps and methods involved in preparing skin tissues for three-dimensional volumetric imaging, highlighting its potential to provide detailed insights into skin structure not possible with traditional 2D histology, but reports no new findings.

This study found that administering mesenchymal stem cells to UV-exposed mice reduced melanin levels, although the decrease was not statistically significant.

This study found that sericin dressing containing collagen hydrolysate significantly reduced wound healing time and improved scar quality compared to commercial dressing in split-thickness skin graft donor sites.

This review discusses the identification and characteristics of melanocyte stem cells, emphasizing their role in hair pigmentation, greying, and skin repigmentation, but reports no new research findings.

This study observed that skin pigmentation significantly attenuates bioluminescent signals in C57Bl/6 mice, complicating quantitative optical imaging and requiring consideration in experimental design.

This study found that overexpression of sPLA2-X in mice was associated with alopecia and hair follicle abnormalities, highlighting its potential role in hair follicle homeostasis.

This article discusses the lack of national credentialing for laser therapy practitioners and emphasizes the need for rigorous self-assessment and expertise, particularly when treating patients with darker skin, without presenting new research results.

This study found that phenyl-imidazole sulfonamide derivatives, particularly ISCK03, inhibited c-kit signaling and promoted depigmentation in various experimental settings, suggesting potential use as skin-whitening agents.

This research found that spontaneous and depilation-induced hair growth result in biologically distinct telogen phases in murine skin, with variations in thickness, pigment content, and hair follicle composition.

In this study, silencing BMAL1 and PER1 genes increased melanogenic activity in follicular and epidermal melanocytes, suggesting that peripheral circadian clocks may regulate melanin pigmentation.

Vitamin B12 deficiency can cause skin darkening and increased blood vessels, but treatment can improve symptoms.