Study on Skin Care and Whitening Effects of Collagen Oligopeptides from Puffer Skin

This study found that collagen and its compound may have antioxidant effects and reduce melanin in guinea pigs, while increasing skin moisture and hydroxyproline content in mice.

This review highlights research reporting that oral collagen peptide supplements are effective in enhancing skin elasticity, hydration, and reducing wrinkles, although results vary across studies. Oral supplementation was generally well-tolerated, and further investigation is needed to optimize formulations and explore topical application challenges.

This study discusses the effects of collagen hydrolysates and the dipeptide Pro-Hyp on gene expression related to hair and epidermis development in mouse skin and reports no new clinical results.

In this study, recombinant type III collagen was found to promote fibroblast proliferation and migration, suggesting potential anti-aging and repairing effects, although it was only effective in significantly inhibiting IL-6, not TNF-α, secretion.

This study found that oral collagen peptides increased the expression of genes related to epidermal and hair cycle development in hairless mouse skin.