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The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Apoptosis is essential for human skin development and forming a functional epidermis.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Different types of skin cells play specific roles in development, healing, and cancer.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Different types of stem cells and their environments are key to skin repair and maintenance.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Fat cells in the skin help start healing and form important repair cells after injury.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Fatty acid transport protein 4 is essential for skin and hair development.

Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.

Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Hair follicle regeneration needs special conditions and young cells.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.