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Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.

Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Acanthosis nigricans is a skin condition that may indicate a higher risk for insulin resistance and type 2 diabetes, and more research is needed to understand and treat it.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Finasteride delivery through skin improved using invasomes and iontophoresis.

Some patients with severe alopecia areata developed skin darkening from their treatment, which may indicate a less effective response to the therapy.

Acne is a chronic skin condition not caused by poor hygiene or diet, and it requires long-term treatment and patient education.

Psychotropic medications can cause skin problems, including serious conditions, and patients should be monitored closely.

Use some skin medications with caution during pregnancy; avoid strong steroids, certain eczema treatments, and systemic retinoids, but many topical treatments and nasal sprays are safe.

Antibiotics often cause skin reactions, making them a major health concern.

Retinoids are effective for skin conditions like severe acne and psoriasis but must be used with caution due to potential side effects and risks during pregnancy.

Newer retinoid drugs are effective for skin conditions but have significant side effects.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.

Excipients greatly affect how well curcumin nanocrystals penetrate the skin and target hair follicles.

Some chemicals absorbed through the skin can cause serious health problems.

The document concludes that various dermatological treatments and drugs can cause skin reactions and side effects.

Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.

Polycystic Ovary Syndrome can cause hair loss and skin issues, and early treatment is important for preventing complications.

Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

The document concluded that various dermatological treatments have different effectiveness and side effects, with some causing irritation, allergic reactions, or systemic effects.

Treating melasma in men is difficult, especially for the deeper skin layers, and may need more than just topical treatments.

Scientists created tiny particles loaded with a hair growth drug, minoxidil, that specifically target hair follicles and skin cells to potentially improve hair growth.

Lasers are effective and safe for various medical treatments, including cancer, wound healing, and skin conditions.

Older hair follicle stem cells have a reduced ability to renew themselves, leading to more hair loss.

MCPIP1 in myeloid cells is important for skin cancer development and healthy hair growth.

Both Th1 and Th2 immune responses are increased in alopecia areata, with Th2 response more strongly linked to how severe the disease is.

Both skin products were equally effective in improving facial discoloration and skin quality.