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Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Scientists have found a way to create hair follicles from skin cells of newborn mice, which can grow and cycle naturally when injected into adult mouse skin.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Sulforaphane from broccoli can help protect skin from sun damage.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.

Bioprinting could improve wound healing but needs more development to match real skin.

Turmeric may have benefits for skin health, but more research is needed to confirm its effectiveness.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.

Pregnancy can cause skin pigmentation, stretch marks, and changes in hair, nails, and sweat glands, with most resolving after birth.

Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.

Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.

Hair follicle regeneration needs special conditions and young cells.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Applying a specific inhibitor lightens skin and hair color.

Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Keratins are important for skin cell health and their problems can cause diseases.

Wound dressing absorbs fluid, regenerates hair follicles, and heals skin burns.

A 3-month stay in space causes skin thinning, disrupts hair growth, and changes muscle-related genes in mice.

Changes in skin microbes play a role in some skin diseases and could lead to new treatments.