89 citations,
March 1996 in “Proceedings of the National Academy of Sciences” CD18-deficient mice developed psoriasis-like skin disease, useful for studying inflammatory skin disorders.
5 citations,
August 2011 in “Dermatologic Surgery” Artificial dermis used for hair transplantation can reconstruct scalp defects effectively without the need for tissue expansion.
55 citations,
December 1987 in “Archives of Dermatology” Two enzyme defects in biotin metabolism cause severe skin, hair, and metabolic issues.
April 2010 in “The journal of immunology/The Journal of immunology” FoxN1 gene is crucial for proper thymus structure and normal skin appearance.
Local flaps are effective for covering small to large scalp and forehead defects with good cosmetic results.
The chapter concludes that certain skin diseases in bovines cause symmetrical, non-painful lesions and temporary hair loss due to stress.
June 2017 in “International Journal of Periodontics & Restorative Dentistry” Using skin grafts from behind the ear for oral surgery in two patients with jaw injuries led to successful healing and good results.
7 citations,
November 2014 in “Histochemistry and Cell Biology” The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.
July 2012 in “Dermatologic Surgery” The author believes artificial dermis might not be the best first option for hair transplant surgeons when other surgical choices exist for scalp reconstruction.
18 citations,
March 2018 in “Archives of Plastic Surgery” The superficial temporal artery flap is a reliable method for reconstructing complex facial defects with minimal complications.
7 citations,
January 2009 in “Biological & pharmaceutical bulletin” Ferrous Ferric Chloride may improve skin cell function and increase hair growth in mice.
88 citations,
October 1983 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Patients with this syndrome can have different responses and worsening resistance to treatment over time.
48 citations,
March 2010 in “PloS one” C/EBPalpha and C/EBPbeta are crucial for normal skin and oil gland cell development in adult mice.
35 citations,
January 2013 in “The Journal of experimental medicine/The journal of experimental medicine” CD98hc's role in skin health decreases with age.
32 citations,
September 2018 in “Journal of pharmaceutical sciences” The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.
27 citations,
February 1988 in “Journal of the American Academy of Dermatology” The skin condition Ulerythema ophryogenes did not improve with treatment in a patient with other birth defects.
18 citations,
October 2018 in “Journal of The American Academy of Dermatology” Some skin medications can harm male fertility, but they don't seem to cause birth defects from father's exposure.
7 citations,
July 1975 in “Acta dermato-venereologica” A patient with Rothmund-Thomson syndrome showed skin changes, hair loss, and dental defects but no cataracts or skeletal issues.
January 2016 in “Journal of Investigative Dermatology” Some cells may slow melanoma growth, a protein could affect skin pigmentation, a gene-silencing method might treat hair defects, skin bacteria changes likely result from eczema, and a defensin protein could help treat multiple sclerosis.
238 citations,
March 2013 in “Development” Fat cells help recruit healing cells and build skin structure during wound healing.
106 citations,
October 2016 in “Cell Stem Cell” PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
96 citations,
July 2014 in “Cold Spring Harbor Perspectives in Medicine” The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.
22 citations,
January 1985 in “Journal of Human Evolution/Journal of human evolution” Human skin and hair color variation is mainly due to melanin produced by a few genes, with melanin protecting against sun damage.
18 citations,
July 2010 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.
16 citations,
December 2006 in “Expert Review of Dermatology” Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.
3 citations,
December 1987 in “The Journal of Dermatologic Surgery and Oncology” Understanding facial anatomy and aesthetics is key for good functional and cosmetic outcomes after tumor removal surgery on the forehead and eyebrow.
2 citations,
January 2023 in “Frontiers in Genetics” Overexpressing ovine β-catenin in mice skin increases hair follicle density and growth.
1 citations,
April 2023 in “International journal of molecular sciences” Certain skin proteins can form anchoring structures without the protein AMACO.
January 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” The gene Ascl4 is not necessary for the development of hair, teeth, or mammary glands.
January 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.