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Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

Alopecia is a key indicator of thallium poisoning.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

New topical antifungals and delivery systems are improving treatment for fungal skin infections, but patient education and prevention are key.

Finasteride may cause long-lasting sexual side effects.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

Hair loss linked to higher heart disease risk in both men and women.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.

The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

Drospirenone is a unique progestin with anti-water retention and potential blood pressure benefits, used in birth control and hormone therapy.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.