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Young female Australian fur seals are losing hair due to low tyrosine and zinc levels and high pollution exposure.

Climate-related nutritional stress may cause hair loss in juvenile male Guadalupe fur seals.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Men, particularly those with hair loss, are more likely to get the virus, and those with prostate cancer may have milder symptoms. Testosterone's role in the disease is unclear, and the virus doesn't seem to harm male fertility. Women with PCOS might be at higher risk. More research is needed.

HSD3B1 gene variant and being overweight linked to hair loss in women with polycystic ovary syndrome.

Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Men with higher androgen levels may have severe COVID-19 symptoms, but those on antiandrogen therapy are less likely to contract the virus and have milder symptoms. Anti-androgen drugs could potentially treat COVID-19, but more research is needed.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Anabolic steroid users may face higher risk of severe COVID-19.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Hair growth is influenced by factors like genetics and nutrition, and more research is needed to understand hair loss and growth mechanisms.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Managing side effects of endocrine therapy is crucial to improve adherence and survival in breast cancer patients.

Finasteride effectively treats BPH, but needs more trials to understand potential.

The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Effective treatments for spinal and bulbar muscular atrophy are not yet available; more research is needed.

A natural steroid in the body may protect against eye damage in glaucoma.