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The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

A new method accurately measures steroid hormones in a few hair strands and could help study chronic stress and hair loss.

Male C57BL/6 mice show age-related fluctuations in certain hormones and their ratios in both blood and hair.

Gonadal hormones significantly affect the severity of alopecia areata in mice.

Chromosomal differences affect how muscle cells respond to testosterone.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

The method accurately measures 19 steroid hormones in human blood and urine using a small sample and is suitable for large-scale monitoring.

The cause of Frontal fibrosing alopecia, a type of hair loss, is complex, likely involving immune responses and genetics, but is not fully understood.

The method can measure multiple steroids in human hair to study long-term steroid metabolism, especially in newborns and children.

Testosterone is linked to cardiovascular risk factors and stroke, but its exact role is unclear.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

High testosterone levels in 20% of the women studied may indicate PCOS, while 80% had low levels with potential health impacts.

SHBG may be a useful early indicator and treatment target for PCOS.

Men and women react differently to opioids, with hormones potentially influencing these differences.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Overweight women with PCOS have higher levels of certain hormones that could indicate a higher risk of heart and metabolic problems.

Hormone imbalances can cause specific skin changes, which may help in early detection of endocrine disorders.

Some ovarian tumors can cause masculinization, and it's important to check for various causes when this symptom is present.

The levonorgestrel implant increases free testosterone and lowers SHBG more than DMPA-IM and the copper IUD.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

A 5 mg dose of transdermal testosterone cream effectively restores testosterone levels in postmenopausal women.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.