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The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Women may need different blood pressure guidelines than men for heart disease prevention.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Early hormones shape sex-specific differences in rat glands.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Sex hormones affect brain injury differently in males and females.

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

Testosterone is linked to cardiovascular risk factors and stroke, but its exact role is unclear.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Young HS patients often have other physical and mental health issues, and research on HS covers a wide range of topics including genetics, triggers, treatments, and the need for more data.

Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

The document concludes that there is a significant lack of reporting on the sex and age of cells in skin research, which could affect clinical trials and treatments.

Gendered social factors, not just biology, contribute to sex differences in adverse drug events.

Men prefer less invasive cosmetic procedures and need different treatment approaches than women.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Men and women get COVID-19 at similar rates, but men tend to get sicker and have a higher risk of dying, while women usually have stronger immune responses and vaccine reactions.

A high-fat diet caused severe health problems in female macaques but was reversible with a normal diet, while male macaques reacted differently.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Many COVID-19 patients have long-term symptoms, especially women, but certain medications may help reduce these symptoms.

Retinoic acid affects male and female muscle energy use and function differently.

Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.

Hormones and genes affect hair growth and male baldness.

Men are more likely to have larger basal cell carcinomas and squamous cell carcinomas, while women have more superficial basal cell carcinomas and tumors on their legs and central face.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Regulating certain sex hormones may help delay facial aging.