research Ophthalmologic Features of Thallium Poisoning
Thallium poisoning can cause serious eye problems and other severe health issues.
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research Discoid Lupus Erythematosus Skin Lesion Distribution and Characteristics in Black Patients: A Retrospective Cohort Study
Black patients with discoid lupus erythematosus have more severe skin damage and higher chances of dyspigmentation, scalp, and ear involvement.
research Histologic Study of the Regeneration Process of Human Hair Follicles Grafted onto SCID Mice after Bulb Amputation
Human hair follicles can regenerate and recover after severe injury by going through a brief abnormal resting phase before growing again.
research Clinical Experiences on Alopecia Areata Treatment with Tofacitinib: A Study of 63 Patients
Tofacitinib is effective and safe for long-term treatment of severe alopecia areata, with many patients achieving complete hair regrowth.
research Association of Type 2 Diabetes With Central-Scalp Hair Loss in a Large Cohort Study of African American Women
Type 2 diabetes may increase the risk of severe hair loss in African American women.
research Combination Therapy with Zinc Gluconate and PUVA for Alopecia Areata Totalis: An Adjunctive but Crucial Role of Zinc Supplementation
Zinc supplementation may be an important part of treating severe hair loss.
research Case 21-2012
The patient was diagnosed with anorexia nervosa and severe malnutrition, requiring urgent refeeding and monitoring.
research Menkes Syndrome Presenting as Myoclonic Seizures: Neuroimaging and EEG Observations
An 11-month-old boy with Menkes disease had severe brain shrinkage and abnormal blood vessels, and didn't respond well to treatment.
research Scalp Psoriasiform Contact Dermatitis with Acute Telogen Effluvium Due to Topical Minoxidil Treatment
Minoxidil treatment for hair loss can cause scalp allergy and severe hair loss.
research A Japanese Case of Ichthyosis Follicularis with Atrichia and Photophobia Syndrome with an MBTPS2 Mutation
A Japanese patient with IFAP syndrome had a severe MBTPS2 gene mutation but showed milder symptoms than previously observed cases.
research Cyclosporine With and Without Systemic Corticosteroids in Treatment of Alopecia Areata: A Systematic Review
Cyclosporine combined with corticosteroids is more effective for severe alopecia areata than cyclosporine alone.
research Man-Made Disease: Clinical Manifestations of Low Phenylalanine Levels in an Inadequately Treated Phenylketonuria Patient and Mouse Study
Proper diet management is crucial for phenylketonuria patients to avoid severe health issues.
research Acne Vulgaris
Oral isotretinoin was recommended for a 21-year-old woman with severe acne.
research Intramuscular Triamcinolone Acetonide: An Undervalued Option for Refractory Alopecia Areata
Intramuscular triamcinolone acetonide is an effective treatment for severe alopecia areata, especially in males.
research Alopecia Areata in a Renal Transplant Recipient on Cyclosporin
A kidney transplant patient on cyclosporin experienced unexpected severe hair loss, which improved with treatment adjustments.
research Persistent Adverse Effects of Antidepressants
Antidepressants can cause long-term side effects like severe withdrawal symptoms and sexual dysfunction, which can last for months or years after stopping the medication.
research Comparison of the Treatment Outcome of Oral Tofacitinib with Other Conventional Therapies in Refractory Alopecia Totalis and Universalis: A Retrospective Study
Tofacitinib works better and is more tolerable for severe alopecia than conventional treatments and DPCP immunotherapy.
research Australian Resources for Ethical Participatory Processes in Public Health Research
PRP injections may be an effective treatment for severe hair loss.
research Acne and Hirsutism in Teenagers
Acne and increased body hair in teenage girls are normal but severe cases may need hormone evaluation and treatment can prevent diabetes linked to PCO.
research Scalp Involvement in Pemphigus: A Prognostic Marker
Scalp involvement in pemphigus means the disease is more severe and harder to treat.
research Polymorphic CAG Repeat Numbers in the Androgen Receptor Gene of Female Pattern Hair Loss Patients
Longer CAG repeats in gene linked to more severe hair loss in females.
research Newborn Screening for Biotinidase Deficiency: Pilot Study and Follow-Up of Identified Cases
Newborn screening for biotinidase deficiency is effective in preventing severe complications.
research Short Versus Long Scalp Flaps in the Treatment of Male Pattern Baldness
Short scalp flaps are easier but not good for severe baldness; Juri flaps are complex but better for density and coverage.
research Sublingual Tofacitinib for Alopecia Areata: A Roll-Over Pilot Clinical Trial and Analysis of Pharmacokinetics
The trial showed that a new under-the-tongue treatment for severe hair loss was somewhat effective in a small group of people.
research MAIT Cells in COVID-19: Heroes, Villains, or Both?
MAIT cells may help fight COVID-19 but also contribute to severe inflammation.
research Fulminant Systemic Vasculitis in Systemic Lupus Erythematosus: Case Report and Review of the Literature
Early diagnosis and quick treatment are crucial for severe lupus cases.
research Therapeutic Hotline: Effectiveness of the Association of Cetirizine and Topical Steroids in Lichen Planus Pilaris - An Open-Label Clinical Trial
Combining cetirizine and topical steroids can effectively manage severe lichen planus pilaris.
research Smoothened Receptor Inhibitor Vismodegib for the Treatment of Basal Cell Carcinoma: A Retrospective Analysis of Efficacy and Side Effects
Vismodegib is effective for basal cell carcinoma but has severe side effects.
research Chronological Clinicopathological Characterization of Rapidly Progressive Alopecia Areata Resistant to Multiple Intravenous Corticosteroid Pulse Therapies: An Implication for Improving Efficacy
Current corticosteroid pulse therapy is not very effective for severe rapidly progressive alopecia areata.
research Evaluation of Trichodynia During Chemotherapy or Tamoxifen Treatment in Breast Cancer Patients
Hair and scalp pain is more common and severe in breast cancer patients on chemotherapy than those on tamoxifen.