research Identification and Characterization of a Novel Pathogenic Mutation in the Human Lipodystrophy Gene AGPAT2
A new mutation in the AGPAT2 gene causes severe fat tissue loss and related health issues by reducing the protein's levels.
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research Rash Morphology as a Predictor of COVID-19 Severity: A Systematic Review of the Cutaneous Manifestations of COVID-19
Certain types of rashes in COVID-19 patients may indicate more severe illness and higher risk of death.
research Postpartum Telogen Effluvium
Only about 20% of women have hair loss after childbirth severe enough to be considered clinically significant.
research Acquired Constriction Ring Syndrome as a Cause of Inconsolable Crying in a Child: A Case Report
A hair tightly wrapped around a toddler's toe caused severe crying and was treated by surgery.
research Case Report of Novel Combination of Anthralin and Calcipotriene Leading to Trichologic Response in Alopecia Areata
A new mix of anthralin and calcipotriene might help treat severe hair loss.
research Association of Autologous Fat Injection in Facial Artery With Ophthalmological Complications
Injecting minced fat into the facial artery can cause severe eye problems and death, more so than other fat types, and larger amounts increase these risks.
research Case Reports of Cronkhite-Canada Syndrome
Cronkhite-Canada syndrome may be more treatable and less severe than previously thought.
research Pathology in Practice: Pemphigus Vulgaris in a 7-Year-Old Mixed-Breed Dog
A 7-year-old dog with a rare autoimmune disease was euthanized due to severe anemia and poor prognosis.
research Serum Vitamin D Level and Disease Severity of Alopecia Areata: A Meta-Regression Analysis
Lower vitamin D levels might be linked to more severe alopecia areata, but more research is needed to understand if vitamin D can help treat it.
research Familial Hypertriglyceridemia in Pregnancy
HIV-positive pregnant women are more likely to experience severe bleeding, and a pregnant woman with familial hypertriglyceridemia had a successful early delivery with special care.
research Cerebellar Hypoplasia, Hypergonadotrophic Hypogonadism, Retinitis Pigmentosa, Alopecia, Microcephaly, Psychomotor Retardation, and Short Stature: D-CHRAMPS Syndrome
"D-CHRAMPS syndrome" is a newly identified condition with multiple severe symptoms.
research Chemokine C-C Motif Ligand 7 (CCL7), a Biomarker of Atherosclerosis, Is Associated with the Severity of Alopecia Areata: A Preliminary Study
Higher levels of CCL7 are linked to more severe hair loss in alopecia areata patients.
research Alopecia and Severity of COVID-19: A Cross-Sectional Study in Peru
Men with hair loss are more likely to experience moderate to severe COVID-19 symptoms.
research The Role of Tofacitinib in the Management of Alopecia Totalis
Tofacitinib helped regrow hair in a patient with severe hair loss and improved their quality of life without side effects.
research Adipose Tissue Transplant in Recurrent Folliculitis Decalvans
Fat tissue transplant may be an effective new treatment for severe, treatment-resistant hair loss from folliculitis decalvans.
research Anti-Androgen Therapy in Female Adult Acne
Anti-androgens are safe and effective for treating moderate to severe adult female acne.
research Construction of Regulatory Network for Alopecia Areata Progression and Identification of Immune Monitoring Genes Based on Multiple Machine-Learning Algorithms
Researchers found four genes that could help diagnose severe alopecia areata early.
research Cardiac and Renal SARS-CoV-2 Viral Entry Protein Regulation by Androgens and Diet: Implications for Polycystic Ovary Syndrome and COVID-19
Androgens and a high-fat diet may increase the risk of severe COVID-19 in women with PCOS by upregulating certain proteins in the heart and kidneys.
research Two Novel BTD Mutations Causing Profound Biotinidase Deficiency in a Chinese Patient
The study found two new mutations in a Chinese patient with severe biotinidase deficiency.
research Hypomorphic Mutation in the Hairless Gene Accelerates Pruritic Atopic Skin Caused by Feeding a Special Diet to Mice
A mutation in the hairless gene speeds up severe itchy skin in mice on a special diet.
research An Adolescent Girl with Coexisting Ovarian Mature Cystic Teratoma and HAIR-AN Syndrome, an Extreme Subtype of Polycystic Ovarian Syndrome
A teenage girl had both a rare ovarian tumor and a severe form of polycystic ovarian syndrome.
research Correlation Between Serum Granulysin Level and Clinical Activity in Patients with Alopecia Areata Before and After Tofacitinib Therapy
Higher granulysin levels in the blood are linked to more severe hair loss in alopecia areata patients, and these levels decrease after effective treatment.
research Prognostic Factors in Mexican Patients with Patchy and Other Types of Alopecia Areata
Early onset, severe types, nail changes, family history, and body hair loss worsen alopecia areata prognosis; sticking to treatment helps.
research An Open Label Clinical Trial of the JAK Inhibitor Tofacitinib for Alopecia Areata
Tofacitinib helped over half of the patients with severe hair loss regrow at least 50% of their hair.
research First Case of Degenerative Mucinotic Mural Folliculitis in Brazil
A cat in Brazil was found with a severe skin condition linked to feline AIDS.
research Synthetic Hair Implantations Continue; Serious Complications Result
Synthetic hair implants are dangerous and can cause severe infections.
research A Current Diagnostic and Therapeutic Challenge: Tinea Capitis
Early recognition and treatment of tinea capitis are crucial to prevent severe scalp issues and prolonged therapy.
research Suicidal Risk Associated With Finasteride Versus Dutasteride Among Men Treated for Benign Prostatic Hyperplasia: Nationwide Cohort Study
Finasteride may increase the risk of suicide or severe self-harm in men with mood disorders but not in the general population.
research A Case of Eruptive Lichen Spinulosus After Toxic Epidermal Necrolysis
A boy developed a rare skin condition after recovering from a severe skin reaction, and it improved with lotion treatment.
research Refractory Pruritic Fox-Fordyce Disease Successfully Treated With Botulinum Toxin Type A
Botox injections may be a safe and effective way to treat severe, itchy skin disease when other treatments fail.