research Cutaneous Reactions to Recombinant Cytokine Therapy
Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.
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research Tissue Regenerative Delays and Synthetic Lethality in Adult Mice After Combined Deletion of ATR and TRP53
Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.
research Doxil (Caelyx): An Exploratory Study with Pharmacokinetics in Patients with Hormone-Refractory Prostate Cancer
Doxil showed some effectiveness against advanced prostate cancer but caused severe side effects at higher doses.
research The E211 G>A Androgen Receptor Polymorphism Is Associated With a Decreased Risk of Metastatic Prostate Cancer and Androgenetic Alopecia
E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.
research Acquired Zinc Deficiency in Long-Term Parenteral Nutrition: A Case Study
Long-term parenteral nutrition without zinc can cause severe zinc deficiency.
research Lead, Mercury, and Arsenic Poisoning Due to Topical Use of Traditional Chinese Medicines
Traditional Chinese medicines with heavy metals can cause severe poisoning.
research Adverse Reactions to Oral Retinoids: An Update
Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.
research Topical 2% Tofacitinib for Children with Alopecia Areata, Alopecia Totalis, and Alopecia Universalis
Applying 2% tofacitinib cream helped some children with severe hair loss grow back hair.
research Efficacy and Safety of Methotrexate in Alopecia Areata
Methotrexate is a promising and safe treatment for severe alopecia areata, with better results when combined with corticosteroids.
research Hair-Thread Tourniquet Syndrome in an Infant With Bony Erosion
A hair wrapped tightly around an infant's toe caused severe damage, requiring early removal and possibly surgery to prevent worse outcomes like amputation.
research Keratosis Follicularis Spinulosa Decalvans: A Family Study of Seven Male Cases and Six Female Carriers
The study found that males with KFSD had severe skin and eye symptoms, while female carriers had milder symptoms.
research Lack of Efficacy of Topical Latanoprost in the Treatment of Eyebrow Alopecia Areata
Topical latanoprost doesn't effectively regrow hair in severe eyebrow alopecia areata cases.
research Treatment-Resistant Alopecia Areata: Response to Combination Therapy with Minoxidil Plus Anthralin
Using minoxidil and anthralin together can improve hair regrowth in severe alopecia areata patients who didn't respond to individual treatments.
research Allergic and Irritant Contact Dermatitis Compared in the Treatment of Alopecia Totalis and Universalis: A Comparison of the Value of Topical Diphencyprone and Tretinoin Gel
DPCP is more effective than tretinoin gel for treating severe alopecia.
research Repurposing Existing Drugs for COVID-19: An Endocrinology Perspective
Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.
research Ceramic Flat Irons: Improper Use Leading to Acquired Trichorrhexis Nodosa
Improper use of ceramic flat irons can cause severe hair damage.
research Alopecia in Crash Dieters
Crash dieting can cause hair loss due to severe calorie restriction.
research Sex-Bias in COVID-19-Associated Illness Severity and Mortality in Cancer Patients: A Systematic Review and Meta-Analysis
Male cancer patients have a higher risk of severe illness and death from COVID-19 than female patients.
research Decreased CD200R Expression on Monocyte-Derived Macrophages Correlates with Th17/Treg Imbalance and Disease Activity in Rheumatoid Arthritis Patients
Lower CD200R1 on certain immune cells is linked to more severe rheumatoid arthritis and immune imbalance.
research A Novel Therapeutic Paradigm for Patients with Extensive Alopecia Areata
New treatments targeting immune pathways show promise for severe hair loss but need more research for safety and effectiveness.
research Endocrinological Evaluation and Hormonal Therapy for Women with Difficult Acne
Hormonal therapy is a good option for women with severe acne, especially when there's a chance of hormone imbalance.
research Clinical Symptoms of Hyperandrogenic Women Diagnosed with COVID-19
Women with high androgen levels may have more severe COVID-19 symptoms.
research Alopecia Areata: A Long-Term Follow-Up Study of 104 Patients
Older age at onset of alopecia areata leads to less severe and shorter episodes, with most patients experiencing significant hair regrowth.
research The Use of Photodynamic Therapy for Treatment of Acne Vulgaris
Photodynamic Therapy is an effective treatment for mild to severe acne.
research Women Who Present With Female Pattern Hair Loss Tend To Underestimate The Severity Of Their Hair Loss
Women with female pattern hair loss often underestimate how severe it is.
research Prognostic Factors in Methylprednisolone Pulse Therapy for Alopecia Areata
Methylprednisolone pulse therapy works best for recent and specific types of severe alopecia areata.
research Bilateral Half-Head Comparison of 1% Anthralin Ointment in Children with Alopecia Areata
1% anthralin ointment is effective and safe for treating severe alopecia areata in children.
research Treatment Effects of Intradermal Botulinum Toxin Type A Injection on Alopecia Areata
Botulinum toxin type A injections are not effective for severe alopecia areata.
research Combination Therapy With Oral PUVA and Corticosteroid for Recalcitrant Alopecia Areata
The combination of oral PUVA and corticosteroids helps regrow hair in severe alopecia areata.
research Presumed Ocular Candidiasis in Drug Misusers After Intravenous Use of Oral High Dose Buprenorphine (Subutex)
Drug misuse can cause serious eye infections and other severe side effects.