research Tofacitinib for the Treatment of Severe Alopecia Areata in Adults and Adolescents
Tofacitinib shows promise for treating severe hair loss in adults and teens, with many experiencing regrowth, but hair loss returns when treatment stops.
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research Breakdown of Immune Tolerance in AIRE-Deficient Rats Induces a Severe Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy–Like Autoimmune Disease
AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
research Treatment of Severe Alopecia Areata with Baricitinib
Baricitinib helped a woman with severe hair loss regrow almost all her hair without side effects.
research Combined Oral Contraception and Bicalutamide in Polycystic Ovary Syndrome and Severe Hirsutism: A Double-Blind Randomized Controlled Trial
Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.
research Combination Tofacitinib and Oral Minoxidil Treatment for Severe Alopecia Areata
Tofacitinib and oral minoxidil together effectively regrow hair in severe alopecia areata patients.
research Total Glucosides of Paeony Capsule Plus Compound Glycyrrhizin Tablets for the Treatment of Severe Alopecia Areata in Children: A Randomized Controlled Trial
TGPC plus CGT is effective and safe for treating severe alopecia areata in children.
research Combination of Low-Dose Isotretinoin and Pulsed Oral Azithromycin in the Management of Moderate to Severe Acne
Low-dose isotretinoin combined with pulsed azithromycin cleared acne in most patients, with mild side effects.
research A Medicinal and Edible Formula YH0618 Ameliorates the Toxicity Induced by Doxorubicin via Regulating the Expression of Bax/Bcl-2 and FOXO4
The formula YH0618 can reduce the harmful side effects of the chemotherapy drug Doxorubicin and protect healthy cells.
research Alopecia in Association with Severe Seborrhoeic Dermatitis Following Combination Antiretroviral Therapy for Acute Retroviral Syndrome
A man with HIV developed skin and hair issues after starting HIV treatment, which improved with topical treatment.
research Letters to the Editor: Case Reports and Studies in Dermatology
Careful management of blood thinners is crucial for lupus patients with APS.
research Transtherapy for Moderate to Severe Acne Scars: A Study of Two Cases
Transtherapy significantly improved moderate to severe acne scars without side effects.
research Diagnostic Exercise: Severe Bilaterally Symmetrical Alopecia in a Horse
A horse with severe hair loss was diagnosed with alopecia areata and a yeast infection.
research Hyperpigmentation, Severe Alopecia, and Six Days of Instability in a Case of Severe Methotrexate Hypersensitivity Reaction
A woman had severe reactions to methotrexate, including skin issues and organ problems, but improved after 38 days in the hospital.
research Clinical Experience on Follicular Unit Extraction Megasession for Severe Androgenetic Alopecia
FUE megasession effectively treats severe hair loss with natural-looking results in one operation.
research Safety of Biological Therapies for Severe Asthma: An Analysis of Suspected Adverse Reactions Reported in the WHO Pharmacovigilance Database
Biologics for severe asthma have known side effects, but some new risks need more study.
research Treatments for Moderate-to-Severe Alopecia Areata: A Systematic Narrative Review
Some treatments for severe hair loss work but often have side effects, with baricitinib showing the most promise.
research Letters to the Editor
The letters discussed medical tools, costs, treatment efficacy, and patient care complexities.
research Letter to the Editor Etiquette
Experts discussed sedation, hair transplant techniques, and called for respectful professional communication.
research Baricitinib Withdrawal and Retreatment in Patients With Severe Alopecia Areata
Continuous baricitinib is needed to keep hair regrowth in severe alopecia areata.
research Improvement in Measures of Quality of Life and Symptoms of Anxiety and Depression in Patients with Severe Alopecia Areata Achieving Sustained Scalp Hair Regrowth with Baricitinib
Baricitinib improves quality of life and reduces anxiety and depression in severe alopecia areata patients with hair regrowth.
research Abrocitinib Improved Dupilumab-Resistant Severe Atopic Dermatitis with Comorbid Mild Alopecia Areata in a 12-Year-Old Boy: A Case Report with 1-Year Follow-Up
Abrocitinib effectively treated severe atopic dermatitis and mild alopecia areata in a 12-year-old boy after dupilumab failed.
research A Pediatric Case of Severe Allergic Conjunctivitis with Underlying Alopecia Areata
Early and proper treatment is crucial for children with allergic conjunctivitis to avoid complications.
research Efficient Genome Editing Using CRISPR/Cas9 Ribonucleoprotein Approach in iPS Cells for Recessive Dystrophic Epidermolysis Bullosa
Researchers fixed gene mutations causing a skin disease in stem cells, which then improved skin grafts in mice.
research Biologic: A Double-Edged Sword - A Case of Etanercept-Induced Alopecia Areata in a Patient with Psoriasis Vulgaris
Etanercept, a psoriasis treatment, caused hair loss in a patient.
research Letter to the Editor: Androgenetic Alopecia; Drug Safety and Therapeutic Strategies
Dutasteride is a safe and effective treatment for hair loss.
research Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men
Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
research Identification of Drug-Specific Public TCR Driving Severe Cutaneous Adverse Reactions
Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.
research Spatiotemporal Control of CRISPR/Cas9 Gene Editing
The document concludes that while there are promising methods to control CRISPR/Cas9 gene editing, more research is needed to overcome challenges related to safety and effectiveness for clinical use.
research Ruxolitinib for the Treatment of Severe Alopecia Areata
Ruxolitinib can help regrow hair in severe alopecia areata.
research Profile of Tofacitinib Citrate and Its Potential in the Treatment of Moderate-to-Severe Chronic Plaque Psoriasis
Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.