Improvement in Measures of Quality of Life and Symptoms of Anxiety and Depression in Patients with Severe Alopecia Areata Achieving Sustained Scalp Hair Regrowth with Baricitinib

    June 2024 in “ Dermatology and Therapy
    Brittany G. Craiglow, Yang Won Lee, Sergio Vañó‐Galván, Alexander Egeberg, Yves Dutronc, Frédérick Durand, Evangeline Pierce, Guanglei Yu, Yun-Fei Chen, Arash Mostaghimi
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    TLDR Baricitinib improves quality of life and reduces anxiety and depression in severe alopecia areata patients with hair regrowth.
    The study examined the impact of baricitinib on health-related quality of life (HRQoL) and symptoms of anxiety and depression in patients with severe alopecia areata (AA) over 104 weeks. Patients who achieved sustained scalp hair regrowth during the BRAVE-AA phase III trials reported significant improvements in HRQoL and reductions in anxiety and depression symptoms, highlighting the potential psychosocial benefits of effective AA treatment.
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