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Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

Plasmalogens activate a channel in cells that may stimulate hair growth.

Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.

A substance called 15-deoxy prostaglandin J2 can cause hair follicle cells to die, which might explain how prostaglandin D2 can lead to hair loss.

Melatonin directly affects mouse hair follicles and may influence hair growth.

Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.

Melatonin given to pregnant rabbits improved their babies' fur quality.

Finding functions for unknown GPCRs is hard but key for making new drugs.

CRTH2 antagonists might be useful for treating many conditions because they play a role in immune and inflammation responses.

Targeting the Smoothened receptor shows promise for treating certain cancers.

HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.

Hedgehog signaling is crucial for mammary gland development over hair follicles.

Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.

KLF4 is important for maintaining skin stem cells and helps heal wounds.

Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Black sheep have higher levels of Gnαs and Gnα11 proteins, which may affect their coat color.

Melatonin helps regulate sleep and may aid in treating various health issues.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Eyelid cells share signaling components but differ in pathway activity.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Frizzled receptors are essential for various body development processes and maintaining certain body functions.

Vitamin D and its receptor may help prevent skin cancer.

The vitamin D receptor can act without its usual activating molecule, affecting hair growth and skin cancer, but its full range of actions is not well understood.

Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

CD61 is important for mouse tooth cell growth and works through Lgr5.

WNT10B is linked to cancer development and affects survival and disease progression in various cancers.

Odontogenic keratocysts are caused by abnormal Hedgehog signaling and can lead to tooth and bone issues.