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Alfacalcidiol and metformin together lowered testosterone in women with PCOS, but did not significantly improve acne, hair growth, or pregnancy rates.

PCOS is a common hormonal disorder in women, often involving menstrual issues and increased diabetes risk, managed through lifestyle changes and targeted treatments.

Certain gene variations are linked to a higher risk of severe acne, suggesting a genetic influence on the condition.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Insulin helps heal corneal wounds and nerves in diabetic mice by activating the Wnt signaling pathway.

Women with PCOS have higher androgen levels that decrease with age but are still higher than in women without PCOS.

Long-term testosterone therapy can cause hormone suppression, affect prostate and heart health, and alter physical characteristics, but does not increase prostate cancer risk and needs more research for full risk assessment.

The document concludes that PCOS in adolescents is complex and requires comprehensive care to manage its symptoms and associated health risks.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

HSD3B1 gene variant and being overweight linked to hair loss in women with polycystic ovary syndrome.

Early-onset baldness is linked to genetics, lifestyle, and can indicate higher risk for heart and metabolic diseases, and affects mental health.

The research suggests that the ZP4 gene is linked to egg development in women with PCOS but requires more study to understand its role in infertility.

Men with more vanadium in their blood and who drink less soy milk are more likely to have hair loss.

Hirsutism causes significant psychological distress in women.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Baicalin may help reduce excessive male hormone levels in PCOS.

Some plants with flavonoids may help treat hair loss and promote hair growth.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

Hormonal treatments can improve acne, but they come with potential side effects and risks.

The document concludes that managing PCOS involves treating symptoms, regulating periods, and reducing health risks, with specific medications for fertility and metabolic issues.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

Genes and hormones cause hair loss, with four genes contributing equally.

Adult female acne requires a comprehensive treatment approach, including medical options and lifestyle changes, with attention to psychological well-being.

Hair loss is a common but often unreported side effect of cancer treatments, especially for breast and prostate cancers.

Hair loss is a common side effect of hormone treatments for cancer.

Hair loss is a common, often overlooked side effect of hormone treatments for breast and prostate cancer.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Certain gene variations might be linked to severe acne in women but not in men.