26 citations
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September 2001 in “Journal of Investigative Dermatology” This study found that the serine protease BSSP is strongly expressed in mouse skin during carcinogenesis and is upregulated independently of c-Fos and unaffected by glucocorticoids.
2 citations
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April 1970 in “Archives of Dermatology” This report discusses a case of ichthyosis serpentina, suggesting it as a variant of ichthyosis associated with bamboo hair, although atopy may not be a necessary component.
21 citations
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April 2018 in “The Journal of urology/The journal of urology” This study found that SER120 nasal spray significantly improved nocturia symptoms and quality of life compared to placebo in patients 50 years and older, with both tested doses showing efficacy and an acceptable safety profile over a 12-week period.
July 2023 in “Pharmacognosy Magazine” This study found that Cerasus serrulata extracts, when obtained through specific methods, demonstrate significant antioxidative and antibacterial properties, as well as potential anti-alopecia effects in a mouse model, potentially making them useful supplements for these purposes.
23 citations
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October 2021 in “AAPS PharmSciTech” 5 citations
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August 2012 in “Experimental Dermatology” In this study, Ser516 phosphorylation of Artemis was found predominantly in the outer root sheath keratinocytes of hair follicles, suggesting a role in regulating human epidermal appendages.
June 2024 in “Warta Pengabdian Andalas” In this study, an educational workshop significantly improved the understanding of hair serum among 19- to 22-year-old students, with 92% of participants showing increased knowledge and 96% expressing high interest in learning about hair issues and serum formulation.
3 citations
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January 2018 in “Elsevier eBooks” The abstract discusses that Serenoa repens, a commonly used phytotherapeutic agent, may play a crucial role as an alternative or complementary treatment for lower urinary tract symptoms in patients with benign prostatic hyperplasia, particularly those with mild-to-moderate disease severity.
January 2026 in “Journal of Burn Care & Research” This study found that a sericin-based hydrogel containing Psidium guajava L. extract significantly improved healing of full-thickness burn wounds in mice, with 89.66% wound closure by day 15 compared to 37.16% in controls, and exhibited beneficial effects on inflammation and oxidative stress markers.
2 citations
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September 2025 in “Frontiers in Endocrinology” This review critically evaluates the evidence for SARMs' tissue selectivity and suggests their clinical benefits over traditional androgens are not yet well-supported by robust evidence, underscoring the need for further head-to-head trials.
December 2024 in “Egyptian Journal of Chemistry” This review highlights that Serenoa repens exhibits anti-androgenic and anti-inflammatory activities, potentially alleviating benign prostate hyperplasia symptoms, with phytosterols and fatty acids as key active constituents, while suggesting more research into additional medicinal uses and phytochemicals is needed.
April 2019 in “Journal of Investigative Dermatology” This study reported that mSKPs and DMSCs share similarities in biological characteristics but exhibit distinct transcriptome profiles, with mSKPs being more immune-related and DMSCs more associated with differentiation and disease pathways.
5 citations
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September 2024 in “Stem Cell Research & Therapy” This study found that stem cell transplantation effectively reduced acute inflammation-induced testicular damage, suggesting potential for cell-based therapies in addressing male infertility.
April 2023 in “Pharmacognosy Magazine” In a study using a mouse model, Cerasus serrulata flower extracts significantly increased β-catenin and VEGF expression, promoting hair blackening and suggesting potential as a treatment for premature greying.
October 2025 in “International Journal of Cosmetic Science” This study explored the effects of USPlus® DERM, a bioactive fatty acid extract from Serenoa repens, in promoting hair growth and enhancing hair follicle stem cell stemness in an ex vivo setting, showing potential for both 5‐α reductase-dependent and independent hair loss treatments.
3 citations
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August 2022 in “Pharmaceuticals” This study observed that a self-emulsifying drug delivery system for finasteride significantly enhanced bioavailability in rats compared to commercial tablets, but the formulation was found to be thermodynamically unstable.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that in hidradenitis suppurativa, the proteins SERPINB3/B4 and S100A7/A8/A9 were significantly overexpressed in lesional skin compared to nonlesional skin, suggesting new pathways in the disease's pathogenesis.
36 citations
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January 1994 in “Cell and Tissue Research” September 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study developed a biobased copolymer called SELP::KP, showing improved hair strength, elasticity, and conditioning properties while being a safer alternative to conventional chemical treatments, based on application to human hair in a laboratory setting.
21 citations
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October 2017 in “Cell death and disease” This study found that the absence of the stress-responsive protein Sesn2 increased hair cell susceptibility to gentamicin in the inner ear, indicating Sesn2's potential protective role against aminoglycoside-induced damage.
7 citations
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March 2023 in “European Journal of Dermatology” Using Selenium Disulfide shampoo weekly helps prevent scalp dermatitis flare-ups.
211 citations
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March 2011 in “Journal of Lipid Research” This study reports a novel LC/MS method that separates and analyzes all known ceramide subclasses in human stratum corneum, identifying a new subclass, CER [EOdS], with minimal sample preparation.
30 citations
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December 2011 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that serine 44 in the N-terminal head domain of keratin 17 is phosphorylated in response to various stimuli affecting skin keratinocyte growth, linking K17 up-regulation with growth and stress responses in skin epithelium.
2 citations
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July 2023 in “Phytotherapy Research” This study found that people taking Serenoa repens for more than 14 days had a higher likelihood of serious adverse reactions, particularly when also using multiple or interacting supplements, although higher SR doses were linked to lower risk.
December 2012 in “International Journal of Phytomedicine” This study found that SESA oil and capsules were associated with decreased hair fall and increased hair regeneration in patients with alopecia, without any reported adverse reactions over three months.
This study found that four bacterial isolates from a microbiology laboratory collection demonstrated resistance to selenate, with molecular analysis showing they closely resemble different strains of Bacillus megaterium.
May 2024 in “Journal of colloid and interface science” This study developed a bilayer bionic skin scaffold that mimics the skin's structure to resist microbial invasion and enhance wound healing, with in vivo animal studies showing improved collagen deposition, neovascularization, and hair follicle formation.
1 citations
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March 2014 in “Senses and Sciences” This article describes a clinical case of a 67-year-old patient with telogen effluvium treated with a supplement containing amino acids, vitamin E, iron, and Serenoa repens, but reports no new clinical findings.
2 citations
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September 2025 in “Journal of Clinical Medicine” This review highlights the promise of small extracellular vesicles (sEVs) as biomarkers for sepsis, emphasizing their potential to improve early detection and guide therapeutic decisions by reflecting the immune status and pathogen presence in patients.
1 citations
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November 2021 in “British Journal of Clinical Pharmacology” This case report suggests a potential link between the intake of Serenoa repens, commonly known as Saw palmetto, and the onset of erectile dysfunction.