Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review describes the molecular interactions between androgens and Wnt/ß-catenin signaling in androgenetic alopecia but reports no new experimental or clinical findings; the authors discuss potential Wnt/ß-catenin-targeted treatments for hair growth.

This study suggests that the protease HAT-L4 plays a significant role in maintaining epidermal barrier function to prevent body fluid loss, as its absence in mice led to increased fluid loss and higher mortality.

In this review, researchers evaluated sericin-based drug delivery systems for antimicrobial, anticancer, and neurodegenerative treatments, highlighting its potential benefits and challenges related to molecular variability and formulation stability, suggesting future focus on optimizing extraction and integration with advanced biomedical technologies.

In this study, elevated mRNA levels for serine-rich ultra high sulfur proteins were observed during active hair growth phases in mice, particularly in the forming hair structures and upper skin layers.

This study found that dietary serine levels influence hair follicle stem cells' ability to balance hair regeneration and wound repair, offering insights for potential interventions to accelerate wound healing.

This study suggests that sericin microneedles with antibacterial and directional traction functionalities may enhance infected wound healing by improving skin repair and inhibiting bacterial growth, indicating potential for clinical application.

Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.

This study identified a crucial Gli2-Serpinh1 regulatory axis that regulates fibroblast state transitions during skin wound healing, shedding light on fibroblast heterogeneity and suggesting potential precision regenerative therapies.

This study reports that a widespread founder SERPINB7 mutation underlies Nagashima-type palmoplantar keratosis, which is a common form of palmoplantar keratosis in Asian populations.

This study found that a proprietary saw palmetto extract significantly improved hair growth in men and women with self-perceived thinning hair over a 6-month period, outperforming placebo on key hair growth parameters without any treatment-related adverse events.

In this study, reports from individuals using Serenoa repens indicated a possible post-Serenoa syndrome characterized by persistent sexual and neuropsychiatric symptoms, with causality assessed as 'probable' in 54% of cases, highlighting an underrecognized safety concern that warrants further investigation.

This review discusses the effects of estrogens on skin aging and highlights the potential benefits of estrogen replacement therapy and selective estrogen receptor modulators for improving skin health in postmenopausal women, but reports no new clinical findings.

This study found that sericin dressing containing collagen hydrolysate significantly reduced wound healing time and improved scar quality compared to commercial dressing in split-thickness skin graft donor sites.

In this study, the combination of Serenoa repens extract with Phenolmicin P3 and Bosexil suppositories significantly improved lower urinary tract symptoms and decreased PSA levels in patients with benign prostatic obstruction-related symptoms.

This study found that an Enterobacter isolate demonstrated high resistance to selenate and effective sorption capacity, suggesting potential for bioremediation of selenium-contaminated environments.

This study found that liposterolic extracts of Serenoa repens enhanced hair regeneration and repair in DHT-induced hair loss mouse models, suggesting potential effects comparable to finasteride.

This study found that the extracts of Serenoa repens, when evaluated through chemical, biological, and in silico methods, demonstrated anti-inflammatory, pro-apoptotic, and anti-androgenic activities against prostate cancer cell lines, suggesting potential therapeutic benefits and directing future pharmaceutical development.

This review discusses the efficacy of the lipidosterolic extract of Serenoa repens for treating lower urinary tract symptoms and reports no new clinical results; the authors propose further examination of the existing literature and guidelines.

This study by Gao et al. reports that two nonsteroidal selective androgen receptor modulators, S1 and S4, demonstrated tissue-selective actions in rats, suppressing prostate growth while maintaining muscle growth without altering hormone levels.

This review concludes that global literature supports the lipidosterolic extract of Serenoa repens as efficacious and safe for treating lower urinary tract symptoms, with some studies showing equivalence to common pharmacologic agents.

This study concludes that dietary L-serine supplementation shows promise as a long-term therapy for hereditary sensory and autonomic neuropathy type 1, reducing neurotoxic 1-deoxysphingolipid levels and improving symptoms in severe cases.

This study found that inactivating CerS4 in mouse epidermis disrupts lipid homeostasis and is crucial for maintaining, but not forming, the skin barrier.

This study found that a proprietary saw palmetto (Serenoa repens) extract significantly increased hair growth and reduced hair shedding in men and women with self-perceived thinning hair over a 90-day period, compared to placebo, without reported adverse events.

Ceramide Synthase 4 is crucial for healthy skin barrier function.

This review concludes that the global literature supports the efficacy and safety of lipidosterolic extract of Serenoa repens in treating lower urinary tract symptoms, comparable to alpha-blockers and 5α-reductase inhibitors.

This article outlines the evolving role of cosmetics in enhancing confidence and attractiveness, highlighting their ability to address skin and hair concerns with active ingredient serums.

Serenoa repens extract may help hair growth in both men and women.