5 citations
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February 2013 in “Klinik Psikofarmakoloji Bulteni-bulletin of Clinical Psychopharmacology” This case report observed that an adolescent female experienced hair loss with fluoxetine and sertraline, which resolved with venlafaxine, suggesting potential alopecia as an adverse reaction to these SSRIs.
72 citations
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January 2011 in “Current Pharmaceutical Design” This review discusses the potential role of steroid 5α-reductase inhibitors in treating neuropsychiatric disorders related to dopaminergic hyperreactivity but reports no new clinical results.
20 citations
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September 1983 in “Archives of dermatology” This study observed that minimal doses of the arotinoid RO 13-6298 successfully treated two cases of severe psoriasis and psoriatic arthritis unresponsive to traditional therapies, despite some side effects.
13 citations
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October 2010 in “Seizure” This study reported that extended-release valproate significantly reduced seizure frequency and improved quality of life in epilepsy patients over six months, despite some adverse effects like weight gain and tremor.
10 citations
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October 2016 in “Epilepsy & behavior” In this study, behavioral disturbances were commonly observed with levetiracetam, while somnolence was frequently reported with oxcarbazepine among patients with refractory epilepsy.
2 citations
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March 2020 in “Cns & Neurological Disorders-drug Targets” In this study, researchers analyzed lurasidone's risk profile for treating schizophrenia and bipolar depression, identifying unlisted adverse reactions like hypersexuality, restless leg syndrome, thrombocytopenia, and telogen effluvium, which show probable or possible correlations with the drug.
27 citations
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April 2008 in “Neuroscience Letters” Olanzapine reduces stress-related anxiety in rats when given acutely.
February 2025 in “Iranian journal of pharmaceutical research” September 2023 in “Journal of the American Academy of Dermatology”
June 2021 in “Psychiatria Danubina” The antidepressant escitalopram likely caused hair loss in a patient.
6 citations
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December 2008 in “Clinics in Dermatology” This study presents four cases of delusions of parasitosis and introduces escitalopram as a potential therapy, highlighting its fewer side effects compared to the commonly used pimozide.
April 2017 in “European Psychiatry” This case report describes a 64-year-old woman who developed delusions after starting citalopram, highlighting citalopram-induced psychosis in older adults as a potential but rare side effect.
July 2026 in “Journal of the American Academy of Dermatology” 64 citations
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March 2008 in “Neuropsychopharmacology”
October 2015 in “Elsevier eBooks” Pramipexole can cause side effects like dizziness, sleepiness, hallucinations, and low blood pressure, and it's important to educate patients and keep doses low.
6 citations
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February 2020 in “Journal of Natural Products” In this chemical investigation, cyclospongiaquinone 1 from the sponge Verongula cf. rigida showed strong steroid 5α-reductase inhibitory activity, comparable to that of finasteride.
3 citations
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July 2012 in “Indian Journal of Psychological Medicine” Olanzapine helped a man who thought he had bugs on his skin.
16 citations
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February 2009 in “Clinical neurology and neurosurgery” In this study, patients with epilepsy who switched from immediate-release to extended-release divalproex sodium did not experience significant changes in seizure frequency, but most preferred the new formulation due to a subjective decrease in tremor during daily activities.
2 citations
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July 2023 in “Phytotherapy Research” This study found that people taking Serenoa repens for more than 14 days had a higher likelihood of serious adverse reactions, particularly when also using multiple or interacting supplements, although higher SR doses were linked to lower risk.
January 2026 in “British Journal of Clinical Pharmacology” In this study, reports from individuals using Serenoa repens indicated a possible post-Serenoa syndrome characterized by persistent sexual and neuropsychiatric symptoms, with causality assessed as 'probable' in 54% of cases, highlighting an underrecognized safety concern that warrants further investigation.
12 citations
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October 1978 in “PubMed” This study found that the aromatic retinoic acid derivative Ro 10-9359 provided excellent results in 64% of severe psoriasis patients, especially in those with erythrodermic and pustular types, though relapses and side effects were noted.
39 citations
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January 1977 in “Dermatology” This study found that the retinoic acid derivative Ro 10-9359 cleared psoriasis lesions in over half of the patients, but most experienced side effects, including skin issues and altered liver enzyme levels.
13 citations
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October 2023 in “Pharmaceutics” This study found that an intranasal gel containing risperidone-loaded glycethosomes significantly enhanced drug bioavailability and improved neuroprotective, antioxidant, and anti-inflammatory effects in schizophrenia-induced rats compared to oral therapies, suggesting a promising alternative for schizophrenic patients who struggle with adhering to oral medication.
This study found that in sleep-deprived rats, increased 5α-reductase expression and activity in the prefrontal cortex contributed to psychosis- and mania-like symptoms, which finasteride ameliorated in a dose-dependent manner.
12 citations
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April 2018 in “Physiology & Behavior” In this study, clozapine reduced suicide-related behaviors in a schizophrenia-like mouse model, but its effects on exploratory behavior were counteracted by the neurosteroid inhibitor finasteride.
64 citations
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January 2002 in “American Journal of Clinical Dermatology” This review examines the adverse skin reactions associated with antipsychotic medications and reports no new clinical findings, but suggests discussing management strategies to improve patient compliance.
17 citations
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May 2007 in “Forensic Science Medicine and Pathology” This study reported that clozapine and its metabolite showed a preference for binding to pigmented hair, but were also detectable in non-pigmented hair of patients with Parkinson's, with high correlations between dose and hair concentration.
August 2025 in “medRxiv (Cold Spring Harbor Laboratory)” This study reports that using 5-alpha reductase inhibitors is associated with a 31% increased risk of depression, highlighting that the choice of comparator group significantly affects study results.
27 citations
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January 2017 in “Neuropsychopharmacology” This study found that acute sleep deprivation enhanced 5α-reductase expression and activity in the rat prefrontal cortex, and finasteride treatment reduced associated psychosis- and mania-like behaviors.
35 citations
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August 2004 in “Epilepsy & behavior” In this study, divalproex sodium extended-release was found to be more tolerable and preferred by patients compared to the delayed-release formulation, with improved seizure control and psychiatric symptom relief.