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RXRα is crucial for proper immune response and links diet to immune function.

Sensitive scalp has higher pH, more redness, abnormal sebum, and altered bacterial makeup.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Iron deficiency might contribute to hair loss in women.

ECOHAIR® lotion is effective and safe for improving hair growth and reducing hair loss.

Fibrodysplasia ossificans progressiva is a rare genetic disorder that causes extra bone growth and symptoms of premature aging.

The vitamin D receptor helps maintain hair and bone health even without binding vitamin D.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

MAD2B slows down the growth of skin cells that are important for hair development by interacting with TCF4.

Genetic defects and UV radiation cause skin damage and aging.

Over half of the diabetes patients had skin issues, with fungal infections being most common.

Drug approvals slowed in 2Q22, but notable drugs like Amvuttra, Camzyos, and Olumiant were approved.

The L412F variant of TLR3 is linked to skin infections, more viral infections, and autoimmune issues.

CaBP1 and 2 are necessary for maintaining calcium currents and hearing in inner ear cells.

CaBP1 and CaBP2 are important for continuous hearing by preventing inactivation of calcium currents in ear cells, with CaBP2 also able to restore hearing when reintroduced.

Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.

SH-MSCs gel reduced IL-6 and increased TGF-β, suggesting it could treat alopecia.

Activating TLR3 improves the healing and immune properties of periodontal ligament stem cells.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

The meeting discussed vitamin D3's role in fighting tuberculosis, potential treatments for skin conditions like psoriasis, and hair follicle regeneration as a possible solution for hair loss.

Chickens exposed to loud noise can quickly regain hearing mostly due to repair of the tectorial membrane, not just hair cell regeneration.

Astressin-B can reverse and prevent hair loss in stressed mice.

Men with androgenetic alopecia have oilier and less hydrated scalps, especially in sensitive areas.

KATP channels are important for energy balance and are targeted by drugs for diabetes, hypoglycemia, hypertension, and hair loss.

ERULUS controls root hair growth by regulating cell wall composition and pectin activity.

CaBP1 and CaBP2 are important for maintaining hearing by supporting continuous calcium currents and nerve signaling in the ear.

Men with early balding should be checked for metabolic syndrome, as there's a link between the two.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Certain plants like Aloe vera and Neem are effective and safe for treating various skin conditions.

Advanced human skin models improve drug development and could replace animal testing.