25 citations,
July 2013 in “Environmental Toxicology and Chemistry” Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.
May 2019 in “The Journal of Sexual Medicine” Flibanserin's effectiveness for low sexual desire in premenopausal women may vary based on hormone levels, with normal hormone levels showing better responses.
823 citations,
February 1998 in “Analytical Chemistry” Method detects finasteride in plasma at very low concentrations.
50 citations,
January 2018 in “Acta physiologica” Working night shifts for four days can lower the body's ability to use insulin, which may increase the risk of type 2 diabetes.
7 citations,
June 2020 in “Experimental dermatology” Researchers found that certain lipids, especially vitamin D3, are lower in prematurely grey hair than in pigmented hair.
Toxoplasma gondii infection may increase testosterone levels in males.
2 citations,
May 2021 in “Clinical Pharmacology in Drug Development” Clascoterone is safe for the heart, even at high doses.
40 citations,
January 2013 in “Frontiers in Endocrinology” Finger length ratios are not linked to the number of specific gene repeats affecting testosterone sensitivity.
Genetic analysis of rabbits identified key genes for traits like coat color, body size, and fertility.
105 citations,
February 2011 in “The Journal of Clinical Endocrinology & Metabolism” Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.
28 citations,
May 2018 in “Scientific reports” Exercise improves insulin sensitivity and hormone regulation in PCOS rats.
11 citations,
April 2019 in “International Journal of Molecular Sciences” Certain genetic variations in OCT1 may improve insulin sensitivity with metformin in women with PCOS.
3 citations,
May 2021 in “Molecules” Rosuvastatin improves lipid levels, reduces inflammation, but worsens insulin sensitivity in men with early-onset hair loss.
July 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The Arabidopsis rhd2 mutant is more sensitive to drought because of changes in cell membrane proteins and cell structure.
286 citations,
April 2009 in “The journal of neuroscience/The Journal of neuroscience” TRPA1 is crucial for mechanical sensitivity in skin sensory neurons.
10 citations,
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Human nails and hair follicles have similar gene activity, especially in the cells that contribute to their growth and development.
2 citations,
September 2017 in “Biotechniques/BioTechniques” Researchers created a mouse cell line to study hair growth and test hair growth drugs.
45 citations,
August 1994 in “Journal of Chromatography B: Biomedical Sciences and Applications” Method detects finasteride in plasma and semen with high sensitivity and accuracy.
8 citations,
July 2020 in “BMC genomics” The research found genes that change during cashmere goat hair growth and could help determine the best time to harvest cashmere.
6 citations,
August 2023 in “BMC genomics” The study found that genetic differences related to hair growth and other traits help cashmere goats adapt to high-altitude environments.
1 citations,
August 2023 in “The journal of pharmacology and experimental therapeutics/The Journal of pharmacology and experimental therapeutics” Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.
1 citations,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
12 citations,
May 2017 in “Journal of Dermatological Treatment” Adult acne severity is influenced by stress, skin sensitivity, makeup, stopping oral contraceptives, and requires female-specific treatment guidelines.
122 citations,
July 2005 in “The FASEB journal” Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.
19 citations,
October 2008 in “Journal der Deutschen Dermatologischen Gesellschaft” Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.
16 citations,
July 2007 in “Facial Plastic Surgery Clinics of North America” The document suggests using fat grafting and laser therapy to improve the aging Asian face and hair restoration techniques tailored to Asian hair characteristics, emphasizing natural results and cultural sensitivity.
28 citations,
February 2014 in “Journal of Telemedicine and Telecare” Smartphone-based teledermatology is effective for diagnosing skin diseases in the military with good accuracy.
19 citations,
March 2008 in “Nature clinical practice endocrinology & metabolism” A combined drug and laser treatment improved hirsutism in a PCOS patient, also enhancing her heart health and requiring regular liver and kidney checks.
8 citations,
October 2010 in “Scandinavian Journal of Clinical & Laboratory Investigation” Normal-range ALT levels can indicate metabolic and hormonal imbalances in young women.
6 citations,
June 2018 in “PLOS ONE” The Alopecia Areata Assessment Tool (ALTO) effectively identifies alopecia areata from other hair loss types but needs more validation.