326 citations
,
February 2009 in “The American journal of pathology” This review discusses the role of Lgr5 as a marker for identifying adult stem cells, particularly in the intestine and hair follicles, and reports no clinical results.
35 citations
,
October 2017 in “Signal Transduction and Targeted Therapy” This study found that fibromodulin significantly reduces scar formation and boosts scar strength in rodent and porcine models, suggesting potential for FMOD-based therapies in cutaneous wound repair.
32 citations
,
December 2014 in “Cold Spring Harbor Perspectives in Medicine” This article reviews the role of polarity proteins in epidermal morphogenesis and homeostasis and discusses how their alteration may contribute to skin disease, but reports no new experimental findings.
31 citations
,
May 2015 in “Stem Cell Reports” This research discusses a novel imaging approach in live mice to study stem cell and niche interactions in tissue homeostasis and reports no new results.
20 citations
,
January 2013 in “Cell & Bioscience” This review discusses recent findings on the epigenetic regulation of adult stem cells and cancer stem cells, highlighting shared and distinct features, and reports no new clinical results.
10 citations
,
December 2011 in “Cell Transplantation” This study suggests that cultured human hair follicle cells can potentially recreate epidermis and produce bioengineered hair follicles in a GMP cell factory for regenerative therapy in alopecia.
6 citations
,
January 2016 in “Journal of Stem Cell Research & Therapy” This study found that suppressing Jagged1 in epidermal stem cells disrupted Notch signaling and resulted in poor-quality wound healing, suggesting a potential therapeutic target for improving wound repair.
4 citations
,
June 2019 in “Revista brasileira de ginecologia e obstetrícia” This article discusses the prevalence of hirsutism in women and highlights that many cases exhibit normal androgen levels, suggesting a need for broader diagnostic approaches.
2 citations
,
September 2023 in “International journal of molecular sciences” This review summarizes the roles of matricellular proteins in skin stem cell niches, highlighting their contribution to stem cell fate, self-renewal, and potential implications for wound healing and aging.
1 citations
,
February 2025 in “Scientific Reports” In this study, researchers found that CD4 is expressed on murine K5+ keratinocytes, and its expression is crucial for maintaining epidermal stem cell balance and wound repair capacity, particularly during aging.
June 2026 in “Journal of Cutaneous and Aesthetic Surgery” This study explored professionals' insights on eyebrow transplantation, finding that while the procedure can enhance appearance and confidence, it also carries risks such as potential complications and costs, emphasizing the need for thorough pre-operative consultations.
January 2025 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” This study surveyed German dermatologists about treating children and adolescents with alopecia areata, revealing significant emotional challenges like bullying and low self-esteem, dissatisfaction with available treatments, and a need for both psychological support and new therapeutic guidelines.
February 2024 in “Bioengineering” This study found that a hydrogel formulation containing insulin, chitosan, and hydroxypropyl methyl cellulose improved wound healing in diabetic mice, promoting faster wound closure and organized tissue formation, with in vitro tests showing no cytotoxicity and enhanced cell migration.
Dental procedures and treatments show promise but need more research for conclusive results.
April 2018 in “Journal of Aesthetic Nursing” This editorial highlighted concerns about the newly launched voluntary register for non-surgical cosmetic practitioners in the UK, reporting dissatisfaction from aesthetic doctors, dentists, and nurses who feel it inadequately protects the public by grouping medical professionals with non-medically trained individuals without mandatory regulation.
January 2017 in “Open Journal of Endocrine and Metabolic Diseases” This case report identifies an adolescent with symptoms indicative of Dunnigan-type partial lipodystrophy, emphasizing the need for early diagnosis to manage associated metabolic complications and improve self-esteem.
September 2013 in “Science” Human stem cells can aid stroke recovery, research experiences boost students' career aspirations, minoxidil may reduce cancer spread, a molecule can slow tumor growth, a protein affects water flow in cells, magnesium behaves differently at tiny scales, and a new method detects slow-moving objects.
September 2013 in “Science” This article discusses the Doppler effect as illustrated by the sound of a passing police siren but presents no new research findings.
May 2012 in “The journal of nervous and mental disease” This review discusses various aspects of Impulse Control Disorders, but reports no new clinical findings; the authors highlight existing knowledge gaps and the need for proven treatments.
April 2010 in “Plastic and Reconstructive Surgery” This study demonstrated that multipotential cells grafted onto matrices successfully grew new hair in 92% of mice, suggesting potential future applications in hair restoration using this method.
42 citations
,
January 2017 in “Stem cells international” This study found that while extracellular matrix components like hyaluronic acid promoted larger organoid formation, other matrix components hindered hair follicle germ assembly in an in vitro model.
39 citations
,
April 2015 in “Regeneration” This review discusses the regenerative processes of lizard tails, particularly focusing on the diversity in blastema development across different species, and reports no new findings.
1 citations
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October 2025 in “Colorectal Disease” In this study, cancer patients aged 30 to 50 reported experiencing diagnostic delays, coping through self-advocacy, and facing stigma-related challenges such as alopecia. The authors concluded that improved physician awareness, tailored screening, and addressing stigma are essential for enhancing care for early-onset colorectal cancer patients.
1 citations
,
July 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that centrosome ablation in developing epidermis triggers cell surveillance pathways, resulting in thinner skin and halted hair follicle growth, while later stages of epidermal growth may operate independently of basal progenitor division orientation.
108 citations
,
November 2006 in “The Milbank Quarterly” This article reviews the history and impacts of direct-to-consumer advertising of prescription drugs in the U.S. and reports no new research findings; it discusses implications for health policy debates.
15 citations
,
August 2013 in “Stem Cells and Development” This study proposes a two-step method that may enhance the generation of stem-like epidermal cells with superior proliferation and differentiation potential for skin regeneration.
14 citations
,
March 2020 in “Cold Spring Harbor Perspectives in Biology” This review discusses the flexibility and diversity of tissue stem cell systems, particularly focusing on the motility and ligand distribution of spermatogenic stem cells, without presenting new experimental results.
12 citations
,
August 2016 in “Current opinion in genetics & development” In this study, researchers using the hair paradigm highlighted how periodic patterning and compartmentalization enable diverse regenerative behaviors, including region-specific renewal cycles and emergent properties like regenerative waves in organ populations.
11 citations
,
November 2009 in “Brazilian Journal of Medical and Biological Research” This study found that young C57BL/6 and BALB/c mice exhibit distinct regenerative patterns during ear wound healing, with greater wound closure but less regeneration in middle-aged C57BL/6 mice.
9 citations
,
March 1981 in “Journal of Advertising” This paper reviews deceptive magazine advertising practices, including editors' insights and efforts by industry and government to reduce such ads, and recommends strategies for their elimination.