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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Grafted rodent and human cells can regenerate hair follicles, but efficiency decreases with age.

Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.

Lymphatic vessels are essential for hair follicle growth and skin regeneration.

Hoxc genes control hair growth through Wnt signaling.

New sensor detects minoxidil accurately and effectively.

Chitosan-coated nanoparticles improve skin delivery of hair loss treatments with fewer side effects.

Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.

Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.

Men with baldness at the front and top of their head at age 45 may have a higher risk of aggressive prostate cancer.

The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.

Laser and light treatments can effectively remove hair long-term.

Taking oral testosterone with finasteride or dutasteride doubles testosterone levels, and food slightly affects it.

Stem cell therapy is a promising approach for hair regrowth despite potential side effects.

The document says that treating the root cause of hair follicle damage is crucial to prevent permanent hair loss, and treatment options vary.

Some anticonvulsant drugs can cause skin reactions, ranging from mild to severe, and managing these reactions is important for patient care.

Special nanoparticles increased skin absorption of hair loss treatments with fewer side effects.

Hair absorbs different substances from solutions based on pH levels.

Fetal-maternal stem cells in a mother's hair can help with tissue repair and regeneration long after childbirth.

White hair has less lipid content and absorbs water differently than brown hair.

Hair absorbs alkali bromide salts and water, affecting its structure, with absorption decreasing at higher temperatures.

Combining mood stabilizers with antipsychotics is more effective for treating children with bipolar disorder than using mood stabilizers alone.

Ethinylestradiol/chlormadinone acetate may be an effective and well-tolerated treatment for skin conditions caused by excess androgens.

At-home laser and light devices can safely reduce acne and hair growth when used correctly but are less effective than professional treatments.